TY - JOUR
T1 - Association between coffee and green tea intake and pneumonia among the Japanese elderly
T2 - a case-control study
AU - The Pneumonia in Elderly People Study Group
AU - Kondo, Kyoko
AU - Suzuki, Kanzo
AU - Washio, Masakazu
AU - Ohfuji, Satoko
AU - Adachi, Satoru
AU - Kan, Sakae
AU - Imai, Seiichiro
AU - Yoshimura, Kunihiko
AU - Miyashita, Naoyuki
AU - Fujisawa, Nobumitsu
AU - Maeda, Akiko
AU - Fukushima, Wakaba
AU - Hirota, Yoshio
AU - Suzuki, Kanzo
AU - Washio, Masakazu
AU - Kondo, Kyoko
AU - Ohfuji, Satoko
AU - Maeda, Akiko
AU - Fukushima, Wakaba
AU - Hirota, Yoshio
AU - Adachi, Satoru
AU - Kan, Sakae
AU - Imai, Seiichiro
AU - Yoshimura, Kunihiko
AU - Miyashita, Naoyuki
AU - Fujisawa, Nobumitsu
AU - Kojimahara, Noriko
AU - Ota, Chiharu
AU - Usami, Ikuji
AU - Kato, Munehiro
AU - Yamamoto, Toshinobu
AU - Yamamoto, Kazuhide
AU - Nakanishi, Yoichi
AU - Kitazono, Takanari
AU - Matsumoto, Takafumi
AU - Tashiro, Hideki
AU - Taketomi, Masahiko
AU - Iwanaga, Tomoaki
AU - Nogami, Hiroko
AU - Takano, Koichi
AU - Tonegawa, Ken
AU - Hayashi, Yoshimitsu
AU - Ikeda, Ikuo
AU - Sugiyama, Shigeki
AU - Aoshima, Masahiro
AU - Nakashima, Kei
AU - Nakamori, Yoshitaka
AU - Seida, Yasushi
AU - Kichikawa, Yoshiko
AU - Nakamura, Atsushi
N1 - Funding Information:
This study was supported by Health and Labour Science Research Grants from the Ministry of Health, Labour and Welfare of Japan (Grant H20-SHINKO-IPPAN-003, H26-SHINKO-GYOSEI-SHITEI-003). The funders of the study had no role in study design, data collection, data analysis, data interpretation, or writing of the report. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - A large prospective cohort study in the United States examined the association between coffee intake and overall and cause-specific mortality and showed a inverse association between pneumonia and influenza deaths and coffee intake. In Japan, the mortality rate of pneumonia in elderly people is high, and its prevention is an important issue. The present study investigated the association between coffee and green tea intake and pneumonia among the elderly. The design was a hospital-based case control study. The cases were patients over 65 years old newly diagnosed as pneumonia. As a control, patients with the same sex and age (range of 5 years) who visited the same medical institution around the same time (within 2 months after examination of the case) for a disease other than pneumonia were selected. There were two controls per case. Odds ratio (OR) and 95% confidence interval (CI) for pneumonia of coffee and green tea intake during the past month were calculated using a conditional logistic regression model. A total of 199 cases and 374 controls were enrolled. When compared to those who do not drink coffee, the OR for pneumonia of those who drink less than one cup of coffee per day was 0.69 (95% CI 0.39–1.21), OR of those who drink one cup was 0.67 (0.38–1.18), and OR of those who drink two or more cups was 0.50 (0.28–0.88) (Trend p = 0.024). No association was found between pneumonia and green tea consumption. This study suggested a preventive association between coffee intake over 2 cups per day and pneumonia in the elderly.
AB - A large prospective cohort study in the United States examined the association between coffee intake and overall and cause-specific mortality and showed a inverse association between pneumonia and influenza deaths and coffee intake. In Japan, the mortality rate of pneumonia in elderly people is high, and its prevention is an important issue. The present study investigated the association between coffee and green tea intake and pneumonia among the elderly. The design was a hospital-based case control study. The cases were patients over 65 years old newly diagnosed as pneumonia. As a control, patients with the same sex and age (range of 5 years) who visited the same medical institution around the same time (within 2 months after examination of the case) for a disease other than pneumonia were selected. There were two controls per case. Odds ratio (OR) and 95% confidence interval (CI) for pneumonia of coffee and green tea intake during the past month were calculated using a conditional logistic regression model. A total of 199 cases and 374 controls were enrolled. When compared to those who do not drink coffee, the OR for pneumonia of those who drink less than one cup of coffee per day was 0.69 (95% CI 0.39–1.21), OR of those who drink one cup was 0.67 (0.38–1.18), and OR of those who drink two or more cups was 0.50 (0.28–0.88) (Trend p = 0.024). No association was found between pneumonia and green tea consumption. This study suggested a preventive association between coffee intake over 2 cups per day and pneumonia in the elderly.
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U2 - 10.1038/s41598-021-84348-w
DO - 10.1038/s41598-021-84348-w
M3 - Article
C2 - 33692403
AN - SCOPUS:85102436488
VL - 11
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
IS - 1
M1 - 5570
ER -