Association of dietary patterns with serum adipokines among Japanese: A cross-sectional study

Ikuko Kashino, Akiko Nanri, Kayo Kurotani, Shamima Akter, Kazuki Yasuda, Masao Sato, Hitomi Hayabuchi, Tetsuya Mizoue

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Diet may influence disease risk by modulating adipokines. Although some foods and nutrients have been linked to circulating adipokine levels, little is known about the role of dietary patterns on adipokines. We investigated the association between major dietary patterns and circulating levels of adiponectin, leptin, resistin, visfatin, and plasminogen activator inhibitor-1 (PAI-1) in a working population. Methods: The subjects were 509 employees (296 men and 213 women), aged 20 to 65 years, of two municipal offices. Serum adipokines were measured using a Luminex suspension bead-based multiplexed array. Dietary patterns were derived by using principal component analysis of the consumption of 52 food and beverage items, which were ascertained by a validated diet history questionnaire. Multiple regression analysis was performed to assess the association between dietary pattern scores and adipokine concentrations, with adjustment for potential confounders. Results: Three major dietary patterns were extracted: a Japanese, a Westernized breakfast, and a meat food patterns. Of these, we found significant, inverse associations of the Westernized breakfast pattern, which was characterized by higher intake of confectioneries, bread, and milk and yogurt but lower intake of alcoholic beverages and rice, with serum leptin and PAI-1 concentrations in a fully adjusted model (P for trend=0.04 for both leptin and PAI-1). The other adipokines were not significantly associated with any dietary pattern. Conclusion: The Westernized breakfast dietary pattern may be associated with lower circulating levels of leptin and PAI-1.

Original languageEnglish
Article number58
JournalNutrition Journal
Volume14
Issue number1
DOIs
Publication statusPublished - Jun 11 2015

Fingerprint

Adipokines
Cross-Sectional Studies
Plasminogen Activator Inhibitor 1
Leptin
Breakfast
Serum
Food
Nicotinamide Phosphoribosyltransferase
Diet
Resistin
Food and Beverages
Alcoholic Beverages
Yogurt
Bread
Adiponectin
Principal Component Analysis
Meat
Suspensions
Milk
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Association of dietary patterns with serum adipokines among Japanese : A cross-sectional study. / Kashino, Ikuko; Nanri, Akiko; Kurotani, Kayo; Akter, Shamima; Yasuda, Kazuki; Sato, Masao; Hayabuchi, Hitomi; Mizoue, Tetsuya.

In: Nutrition Journal, Vol. 14, No. 1, 58, 11.06.2015.

Research output: Contribution to journalArticle

Kashino, I, Nanri, A, Kurotani, K, Akter, S, Yasuda, K, Sato, M, Hayabuchi, H & Mizoue, T 2015, 'Association of dietary patterns with serum adipokines among Japanese: A cross-sectional study', Nutrition Journal, vol. 14, no. 1, 58. https://doi.org/10.1186/s12937-015-0046-8
Kashino, Ikuko ; Nanri, Akiko ; Kurotani, Kayo ; Akter, Shamima ; Yasuda, Kazuki ; Sato, Masao ; Hayabuchi, Hitomi ; Mizoue, Tetsuya. / Association of dietary patterns with serum adipokines among Japanese : A cross-sectional study. In: Nutrition Journal. 2015 ; Vol. 14, No. 1.
@article{f19c0cde141c4198af098d9d67351281,
title = "Association of dietary patterns with serum adipokines among Japanese: A cross-sectional study",
abstract = "Background: Diet may influence disease risk by modulating adipokines. Although some foods and nutrients have been linked to circulating adipokine levels, little is known about the role of dietary patterns on adipokines. We investigated the association between major dietary patterns and circulating levels of adiponectin, leptin, resistin, visfatin, and plasminogen activator inhibitor-1 (PAI-1) in a working population. Methods: The subjects were 509 employees (296 men and 213 women), aged 20 to 65 years, of two municipal offices. Serum adipokines were measured using a Luminex suspension bead-based multiplexed array. Dietary patterns were derived by using principal component analysis of the consumption of 52 food and beverage items, which were ascertained by a validated diet history questionnaire. Multiple regression analysis was performed to assess the association between dietary pattern scores and adipokine concentrations, with adjustment for potential confounders. Results: Three major dietary patterns were extracted: a Japanese, a Westernized breakfast, and a meat food patterns. Of these, we found significant, inverse associations of the Westernized breakfast pattern, which was characterized by higher intake of confectioneries, bread, and milk and yogurt but lower intake of alcoholic beverages and rice, with serum leptin and PAI-1 concentrations in a fully adjusted model (P for trend=0.04 for both leptin and PAI-1). The other adipokines were not significantly associated with any dietary pattern. Conclusion: The Westernized breakfast dietary pattern may be associated with lower circulating levels of leptin and PAI-1.",
author = "Ikuko Kashino and Akiko Nanri and Kayo Kurotani and Shamima Akter and Kazuki Yasuda and Masao Sato and Hitomi Hayabuchi and Tetsuya Mizoue",
year = "2015",
month = "6",
day = "11",
doi = "10.1186/s12937-015-0046-8",
language = "English",
volume = "14",
journal = "Nutrition Journal",
issn = "1475-2891",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Association of dietary patterns with serum adipokines among Japanese

T2 - A cross-sectional study

AU - Kashino, Ikuko

AU - Nanri, Akiko

AU - Kurotani, Kayo

AU - Akter, Shamima

AU - Yasuda, Kazuki

AU - Sato, Masao

AU - Hayabuchi, Hitomi

AU - Mizoue, Tetsuya

PY - 2015/6/11

Y1 - 2015/6/11

N2 - Background: Diet may influence disease risk by modulating adipokines. Although some foods and nutrients have been linked to circulating adipokine levels, little is known about the role of dietary patterns on adipokines. We investigated the association between major dietary patterns and circulating levels of adiponectin, leptin, resistin, visfatin, and plasminogen activator inhibitor-1 (PAI-1) in a working population. Methods: The subjects were 509 employees (296 men and 213 women), aged 20 to 65 years, of two municipal offices. Serum adipokines were measured using a Luminex suspension bead-based multiplexed array. Dietary patterns were derived by using principal component analysis of the consumption of 52 food and beverage items, which were ascertained by a validated diet history questionnaire. Multiple regression analysis was performed to assess the association between dietary pattern scores and adipokine concentrations, with adjustment for potential confounders. Results: Three major dietary patterns were extracted: a Japanese, a Westernized breakfast, and a meat food patterns. Of these, we found significant, inverse associations of the Westernized breakfast pattern, which was characterized by higher intake of confectioneries, bread, and milk and yogurt but lower intake of alcoholic beverages and rice, with serum leptin and PAI-1 concentrations in a fully adjusted model (P for trend=0.04 for both leptin and PAI-1). The other adipokines were not significantly associated with any dietary pattern. Conclusion: The Westernized breakfast dietary pattern may be associated with lower circulating levels of leptin and PAI-1.

AB - Background: Diet may influence disease risk by modulating adipokines. Although some foods and nutrients have been linked to circulating adipokine levels, little is known about the role of dietary patterns on adipokines. We investigated the association between major dietary patterns and circulating levels of adiponectin, leptin, resistin, visfatin, and plasminogen activator inhibitor-1 (PAI-1) in a working population. Methods: The subjects were 509 employees (296 men and 213 women), aged 20 to 65 years, of two municipal offices. Serum adipokines were measured using a Luminex suspension bead-based multiplexed array. Dietary patterns were derived by using principal component analysis of the consumption of 52 food and beverage items, which were ascertained by a validated diet history questionnaire. Multiple regression analysis was performed to assess the association between dietary pattern scores and adipokine concentrations, with adjustment for potential confounders. Results: Three major dietary patterns were extracted: a Japanese, a Westernized breakfast, and a meat food patterns. Of these, we found significant, inverse associations of the Westernized breakfast pattern, which was characterized by higher intake of confectioneries, bread, and milk and yogurt but lower intake of alcoholic beverages and rice, with serum leptin and PAI-1 concentrations in a fully adjusted model (P for trend=0.04 for both leptin and PAI-1). The other adipokines were not significantly associated with any dietary pattern. Conclusion: The Westernized breakfast dietary pattern may be associated with lower circulating levels of leptin and PAI-1.

UR - http://www.scopus.com/inward/record.url?scp=84935878357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84935878357&partnerID=8YFLogxK

U2 - 10.1186/s12937-015-0046-8

DO - 10.1186/s12937-015-0046-8

M3 - Article

C2 - 26058488

AN - SCOPUS:84935878357

VL - 14

JO - Nutrition Journal

JF - Nutrition Journal

SN - 1475-2891

IS - 1

M1 - 58

ER -