Associations between day-by-day variability in blood pressure measured at home and antihypertensive drugs: The J-HOME-morning study home

Kazuki Ishikura, Taku Obara, Tetsuo Kato, Masahiro Kikuya, Taku Shibamiya, Takahiro Shinki, Urara Ikeda, Yuka Kobayashi, Hirohito Metoki, Nariyasu Mano, Shinichi Kuriyama, Takayoshi Ohkubo, Yutaka Imai, Makoto Yoshida, S. Aoki, H. Ido, K. Ito, K. Kikuchi, I. Maeda, T. MitoA. Nunokawa, K. Oda, N. Suzuki, Y. Takagawa, K. Tateda, S. Tateda, M. Akimot, G. Tashima, Y. Fujii, G. Onodera, T. Onodera, N. Sugiuchi, Y. Suzuki, R. Domon, T. Hayashi, K. Ishibashi, K. Ito, S. Kataoka, S. Kyogoku, H. Mashiko, K. Matsuo, H. Metoki, Y. Otake, J. Saito, Y. Shishido, A. Takayama, Y. Tanno, S. Toyota, N. Uchida, M. Yambe

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

We identified the factors associated with home blood pressure (BP) variability in 1933 patients treated with hypertensive drugs (mean age, 67 years; women, 55%). Multivariate regression analysis showed that female gender, advanced age, home BP value, and home heart rate variability were positively associated with home BP variability, whereas home heart rate, body mass index, and duration of antihypertensive treatment were negatively associated with home BP variability. Moreover, not being medicated with amlodipine and being medicated with angiotensin II receptor blockers were associated with increased home systolic BP variability only among patients who were treated for less than 12 months.

Original languageEnglish
Pages (from-to)297-304
Number of pages8
JournalClinical and Experimental Hypertension
Volume34
Issue number4
DOIs
Publication statusPublished - Jul 1 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology

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