Asymmetric 1,2-addition of organolithiums to aldimines catalyzed by chiral ligand

Isao Inoue, Mitsuru Shindo, Kenji Koga, Kiyoshi Tomioka

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

An asymmetric 1,2-addition reaction of organolithiums with imines 3, 7 was catalysed by a 0.05-1.3 equivalent of a chiral amino ether 2 to provide the corresponding optically active amines 4, 8.

Original languageEnglish
Pages (from-to)4429-4438
Number of pages10
JournalTetrahedron
Volume50
Issue number15
DOIs
Publication statusPublished - Apr 11 1994
Externally publishedYes

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Addition reactions
Imines
Ether
Amines
Ligands

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Asymmetric 1,2-addition of organolithiums to aldimines catalyzed by chiral ligand. / Inoue, Isao; Shindo, Mitsuru; Koga, Kenji; Tomioka, Kiyoshi.

In: Tetrahedron, Vol. 50, No. 15, 11.04.1994, p. 4429-4438.

Research output: Contribution to journalArticle

Inoue, Isao ; Shindo, Mitsuru ; Koga, Kenji ; Tomioka, Kiyoshi. / Asymmetric 1,2-addition of organolithiums to aldimines catalyzed by chiral ligand. In: Tetrahedron. 1994 ; Vol. 50, No. 15. pp. 4429-4438.
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