Abstract
trans-2,5-Bis(methoxymethoxymethyl)pyrrolidine proved to be an excellent chiral auxiliary for the asymmetric acylation of the corresponding carboxamide enolates and the stereoselective Zn(BH4)2 reduction of the resulting 2-alkyl-3-oxo amides provided a useful alternative to asymmetric aldol reaction.
Original language | English |
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Pages (from-to) | 6015-6016 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 25 |
Issue number | 52 |
DOIs | |
Publication status | Published - 1984 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry