Asymmetric alkynylation of aldehydes catalyzed by an In(III)/BINOL complex

Ryo Takita; Kenichiro Yakura; Takashi Ohshima; Masakatsu Shibasaki

doi:10.1021/ja053946n

Asymmetric alkynylation of aldehydes catalyzed by an In(III)/BINOL complex

Ryo Takita, Kenichiro Yakura, Takashi Ohshima, Masakatsu Shibasaki

Research output: Contribution to journal › Article › peer-review

225 Citations (Scopus)

Abstract

Asymmetric alkynylation of both aromatic and aliphatic aldehydes using catalytic amounts of In(III)/BINOL is described. Dual activation of both substrates due to the "bifunctional character" of the indium(III) catalyst enables a broad range of substrate generality with high enantioselectivity (83 to > 99% ee).

Original language	English
Pages (from-to)	13760-13761
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	127
Issue number	40
DOIs	https://doi.org/10.1021/ja053946n
Publication status	Published - Oct 12 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja053946n

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title = "Asymmetric alkynylation of aldehydes catalyzed by an In(III)/BINOL complex",

abstract = "Asymmetric alkynylation of both aromatic and aliphatic aldehydes using catalytic amounts of In(III)/BINOL is described. Dual activation of both substrates due to the {"}bifunctional character{"} of the indium(III) catalyst enables a broad range of substrate generality with high enantioselectivity (83 to > 99% ee).",

author = "Ryo Takita and Kenichiro Yakura and Takashi Ohshima and Masakatsu Shibasaki",

year = "2005",

month = oct,

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doi = "10.1021/ja053946n",

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volume = "127",

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journal = "Journal of the American Chemical Society",

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publisher = "American Chemical Society",

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TY - JOUR

T1 - Asymmetric alkynylation of aldehydes catalyzed by an In(III)/BINOL complex

AU - Takita, Ryo

AU - Yakura, Kenichiro

AU - Ohshima, Takashi

AU - Shibasaki, Masakatsu

PY - 2005/10/12

Y1 - 2005/10/12

N2 - Asymmetric alkynylation of both aromatic and aliphatic aldehydes using catalytic amounts of In(III)/BINOL is described. Dual activation of both substrates due to the "bifunctional character" of the indium(III) catalyst enables a broad range of substrate generality with high enantioselectivity (83 to > 99% ee).

AB - Asymmetric alkynylation of both aromatic and aliphatic aldehydes using catalytic amounts of In(III)/BINOL is described. Dual activation of both substrates due to the "bifunctional character" of the indium(III) catalyst enables a broad range of substrate generality with high enantioselectivity (83 to > 99% ee).

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U2 - 10.1021/ja053946n

DO - 10.1021/ja053946n

M3 - Article

C2 - 16201775

AN - SCOPUS:26444539787

SN - 0002-7863

VL - 127

SP - 13760

EP - 13761

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 40

ER -

Asymmetric alkynylation of aldehydes catalyzed by an In(III)/BINOL complex

Abstract

All Science Journal Classification (ASJC) codes

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