Asymmetric double aldol reaction of chiral acetyloxazolidinone

Hiroshi Furuno, Tadashi Inoue, Atsushi Abiko

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Treatment of chiral oxazolidinone with Bu2BOTf (2.5 equiv.) and Et3N (3.0 equiv.) quantitatively produced the doubly borylated enolate, which afforded the double aldol products with high diastereoselectivity after reaction with aldehydes.

Original languageEnglish
Pages (from-to)8297-8299
Number of pages3
JournalTetrahedron Letters
Issue number46
Publication statusPublished - Nov 11 2002


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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