Asymmetric double aldol reaction of chiral acetyloxazolidinone

Hiroshi Furuno, Tadashi Inoue, Atsushi Abiko

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Treatment of chiral oxazolidinone with Bu2BOTf (2.5 equiv.) and Et3N (3.0 equiv.) quantitatively produced the doubly borylated enolate, which afforded the double aldol products with high diastereoselectivity after reaction with aldehydes.

Original languageEnglish
Pages (from-to)8297-8299
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number46
DOIs
Publication statusPublished - Nov 11 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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