Asymmetric hydrosilylation of symmetrical diketones catalyzed by a rhodium complex with trans-chelating chiral diphosphine EtTRAP

Ryoichi Kuwano, Masaya Sawamura, Junya Shirai, Masatoshi Takahashi, Yoshihiko Ito

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Abstract

Asymmetric hydrosilylation of symmetrical diketones with diphenylsilane in the presence of catalytic amount ([substrate]/[catalyst] = 100) of rhodium complex coordinated with trans-chelating chiral phosphine ligand EtTRAP gave corresponding optically active symmetrical diols with high enantiomeric excesses.

Original languageEnglish
Pages (from-to)5239-5242
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number29
DOIs
Publication statusPublished - Jul 17 1995
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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