Asymmetric Michael addition reaction of methyl phenylthioacetate to 2-cyclopentenone catalyzed by chiral crown - KOtBu complexes

Shin Aoki, Shigeki Sasaki, Kenji Koga

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Asymmetric Michael addition reaction of methyl phenylthioacetate (12) to 2-cyclopentenone (11) using chiral crown ether - KOtBu complexes as catalysts is reported. Crown (7) has been found to give 14 of 71%ee (enantiomeric excess).

Original languageEnglish
Pages (from-to)493-495
Number of pages3
JournalHeterocycles
Volume33
Issue number2
Publication statusPublished - Apr 1 1992
Externally publishedYes

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this