Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation

Masato Kitamura; Makoto Tokunaga; Trang Pham; William D. Lubell; Ryoji Noyori

doi:10.1016/00404-0399(50)11355-

Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation

Masato Kitamura, Makoto Tokunaga, Trang Pham, William D. Lubell, Ryoji Noyori

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

BINAP-Ru catalyzed hydrogenation of configurationally labile α-amido β-keto phosphonic esters gives the (R,R)- or (S,S)-α-amido β-hydroxy phosphonic esters in a highly enantio- and diastereoselective manner.

Original language	English
Pages (from-to)	5769-5772
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	32
DOIs	https://doi.org/10.1016/00404-0399(50)11355-
Publication status	Published - Aug 7 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/00404-0399(50)11355-

Cite this

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title = "Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation",

abstract = "BINAP-Ru catalyzed hydrogenation of configurationally labile α-amido β-keto phosphonic esters gives the (R,R)- or (S,S)-α-amido β-hydroxy phosphonic esters in a highly enantio- and diastereoselective manner.",

author = "Masato Kitamura and Makoto Tokunaga and Trang Pham and Lubell, {William D.} and Ryoji Noyori",

year = "1995",

month = aug,

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T1 - Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation

AU - Kitamura, Masato

AU - Tokunaga, Makoto

AU - Pham, Trang

AU - Lubell, William D.

AU - Noyori, Ryoji

PY - 1995/8/7

Y1 - 1995/8/7

N2 - BINAP-Ru catalyzed hydrogenation of configurationally labile α-amido β-keto phosphonic esters gives the (R,R)- or (S,S)-α-amido β-hydroxy phosphonic esters in a highly enantio- and diastereoselective manner.

AB - BINAP-Ru catalyzed hydrogenation of configurationally labile α-amido β-keto phosphonic esters gives the (R,R)- or (S,S)-α-amido β-hydroxy phosphonic esters in a highly enantio- and diastereoselective manner.

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U2 - 10.1016/00404-0399(50)11355-

DO - 10.1016/00404-0399(50)11355-

M3 - Article

AN - SCOPUS:85047671655

SN - 0040-4039

VL - 36

SP - 5769

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -

Asymmetric synthesis of α-amino β-hydroxy phosphonic acids via BINAP-ruthenium catalyzed hydrogenation

Abstract

All Science Journal Classification (ASJC) codes

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