ATP receptors in pain sensation

Kazuhide Inoue; Makoto Tsuda; Schuichi Koizumi

doi:10.1254/fpj.124.228

ATP receptors in pain sensation

Kazuhide Inoue, Makoto Tsuda, Schuichi Koizumi

Trustee(Vice President)

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

We reported that activation of P2X2/3 heteromeric channels in Aδ-DRG neurons causes tactile allodynia and activation of P2X3 in C-fiber causes nocifensive behavior. We also found that tactile allodynia under the chronic pain state requires an activation of P2X4 ionotropic ATP receptor and p38 mitogen-activated protein kinase in spinal microglia.

Original language	English
Pages (from-to)	228-233
Number of pages	6
Journal	Folia Pharmacologica Japonica
Volume	124
Issue number	4
DOIs	https://doi.org/10.1254/fpj.124.228
Publication status	Published - 2004

All Science Journal Classification (ASJC) codes

Pharmacology

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10.1254/fpj.124.228

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title = "ATP receptors in pain sensation",

abstract = "We reported that activation of P2X2/3 heteromeric channels in Aδ-DRG neurons causes tactile allodynia and activation of P2X3 in C-fiber causes nocifensive behavior. We also found that tactile allodynia under the chronic pain state requires an activation of P2X4 ionotropic ATP receptor and p38 mitogen-activated protein kinase in spinal microglia.",

author = "Kazuhide Inoue and Makoto Tsuda and Schuichi Koizumi",

year = "2004",

doi = "10.1254/fpj.124.228",

language = "English",

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pages = "228--233",

journal = "Folia Pharmacologica Japonica",

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publisher = "Japanese Pharmacological Society",

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T1 - ATP receptors in pain sensation

AU - Inoue, Kazuhide

AU - Tsuda, Makoto

AU - Koizumi, Schuichi

PY - 2004

Y1 - 2004

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AB - We reported that activation of P2X2/3 heteromeric channels in Aδ-DRG neurons causes tactile allodynia and activation of P2X3 in C-fiber causes nocifensive behavior. We also found that tactile allodynia under the chronic pain state requires an activation of P2X4 ionotropic ATP receptor and p38 mitogen-activated protein kinase in spinal microglia.

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U2 - 10.1254/fpj.124.228

DO - 10.1254/fpj.124.228

M3 - Review article

C2 - 15467256

AN - SCOPUS:7044226317

SN - 0015-5691

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EP - 233

JO - Folia Pharmacologica Japonica

JF - Folia Pharmacologica Japonica

IS - 4

ER -

ATP receptors in pain sensation

Abstract

All Science Journal Classification (ASJC) codes

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