ATP receptors in pain sensation

Kazuhide Inoue, Makoto Tsuda, Schuichi Koizumi

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

We reported that activation of P2X2/3 heteromeric channels in Aδ-DRG neurons causes tactile allodynia and activation of P2X3 in C-fiber causes nocifensive behavior. We also found that tactile allodynia under the chronic pain state requires an activation of P2X4 ionotropic ATP receptor and p38 mitogen-activated protein kinase in spinal microglia.

Original languageEnglish
Pages (from-to)228-233
Number of pages6
JournalFolia Pharmacologica Japonica
Volume124
Issue number4
DOIs
Publication statusPublished - 2004

All Science Journal Classification (ASJC) codes

  • Pharmacology

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