Abstract
People who stutter (PWS) can reduce their stuttering rates through noise masking and altered auditory feedback; such a response can be attributed to altered auditoryinput, which suggests that abnormal speech processing in PWS results from abnormal processing of auditory input. In order to characterize such abnormalities, we examined the functional and structural changes in the auditory cortices of PWS by using a 306-channel magnetoencephalography system to assess auditory sensory gating (P50m suppression) and tonotopic organization. Additionally, we employed voxel-based morphometry to compare cortical gray matter (GM) volumes on structural MR images. PWS exhibited impaired left auditory sensory gating. The tonotopic organization in the right hemisphere of PWS was expanded compared with that of the controls. Furthermore, PWS showed a significant increase in the GM volume of the right superior temporal gyrus, consistent with the right tonotopic expansion. Accordingly, we suggest that PWS have impaired left auditory sensory gating during basic auditory input processing and that some error signals in the auditory cortex could result in abnormal speech processing. Functional and structural reorganization of the right auditory cortex appears to be a compensatory mechanism for impaired left auditory cortex function in PWS.
| Original language | English |
|---|---|
| Pages (from-to) | 117-121 |
| Number of pages | 5 |
| Journal | Japan Journal of Logopedics and Phoniatrics |
| Volume | 54 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2013 |
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All Science Journal Classification (ASJC) codes
- LPN and LVN
- Speech and Hearing
Cite this
Auditory neuroscience applied to stuttering. / Kikuchi, Yoshikazu; Umezaki, Toshiro; Komune, Shizuo.
In: Japan Journal of Logopedics and Phoniatrics, Vol. 54, No. 2, 01.04.2013, p. 117-121.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Auditory neuroscience applied to stuttering
AU - Kikuchi, Yoshikazu
AU - Umezaki, Toshiro
AU - Komune, Shizuo
PY - 2013/4/1
Y1 - 2013/4/1
N2 - People who stutter (PWS) can reduce their stuttering rates through noise masking and altered auditory feedback; such a response can be attributed to altered auditoryinput, which suggests that abnormal speech processing in PWS results from abnormal processing of auditory input. In order to characterize such abnormalities, we examined the functional and structural changes in the auditory cortices of PWS by using a 306-channel magnetoencephalography system to assess auditory sensory gating (P50m suppression) and tonotopic organization. Additionally, we employed voxel-based morphometry to compare cortical gray matter (GM) volumes on structural MR images. PWS exhibited impaired left auditory sensory gating. The tonotopic organization in the right hemisphere of PWS was expanded compared with that of the controls. Furthermore, PWS showed a significant increase in the GM volume of the right superior temporal gyrus, consistent with the right tonotopic expansion. Accordingly, we suggest that PWS have impaired left auditory sensory gating during basic auditory input processing and that some error signals in the auditory cortex could result in abnormal speech processing. Functional and structural reorganization of the right auditory cortex appears to be a compensatory mechanism for impaired left auditory cortex function in PWS.
AB - People who stutter (PWS) can reduce their stuttering rates through noise masking and altered auditory feedback; such a response can be attributed to altered auditoryinput, which suggests that abnormal speech processing in PWS results from abnormal processing of auditory input. In order to characterize such abnormalities, we examined the functional and structural changes in the auditory cortices of PWS by using a 306-channel magnetoencephalography system to assess auditory sensory gating (P50m suppression) and tonotopic organization. Additionally, we employed voxel-based morphometry to compare cortical gray matter (GM) volumes on structural MR images. PWS exhibited impaired left auditory sensory gating. The tonotopic organization in the right hemisphere of PWS was expanded compared with that of the controls. Furthermore, PWS showed a significant increase in the GM volume of the right superior temporal gyrus, consistent with the right tonotopic expansion. Accordingly, we suggest that PWS have impaired left auditory sensory gating during basic auditory input processing and that some error signals in the auditory cortex could result in abnormal speech processing. Functional and structural reorganization of the right auditory cortex appears to be a compensatory mechanism for impaired left auditory cortex function in PWS.
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U2 - 10.5112/jjlp.54.117
DO - 10.5112/jjlp.54.117
M3 - Article
AN - SCOPUS:84878094902
VL - 54
SP - 117
EP - 121
JO - Japan Journal of Logopedics and Phoniatrics
JF - Japan Journal of Logopedics and Phoniatrics
SN - 0030-2813
IS - 2
ER -