Augmentation of antigen-specific cytotoxicity by concanavalin A at the peak of response to tumor allografts

Yoshinori Shimamoto, Kikuo Nomoto, Kazuto Taniguchi, Chiharu Kubo

Research output: Contribution to journalArticle

Abstract

Antigen-specific cytotoxicity was augmented 24 hr after in vivo or in vitro treatment with concanavalin A at approximately the peak of response to allografted EL-4 cells. Such augmentation appears to require protein synthesis but not cell division. The augmentation may be ascribed to enhanced expression of cytotoxic activity of performed effector T cells rather than an increase in the number of effector cells.

Original languageEnglish
Pages (from-to)204-210
Number of pages7
JournalCellular Immunology
Volume47
Issue number1
DOIs
Publication statusPublished - Sep 15 1979

All Science Journal Classification (ASJC) codes

  • Immunology

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