Autoimmune cholangiopathy associated with rheumatoid arthritis

Hisanobu Ogata, H. Tsuji, M. Hashiguchi, K. Azuma, J. Shimono, M. Fujishima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We herein describe a patient with autoimmune cholangiopathy complicated with rheumatoid arthritis. A 58-year-old female was admitted to our hospital due to complications of arthralgia in her fingers, shoulders, elbows, knees and ankles. She presented with abnormally elevated levels of transaminases, alkaline phosphatase and was also negative for hepatitis B virus, hepatitis C virus and the serum mitochondrial antibody test, but had high titers of serum antinuclear antibody, rheumatoid factor and rheumatoid arthritis hemagglutination. A liver biopsy specimen showed chronic non-suppurative destructive cholangitis. She was thus diagnosed to have autoimmune cholangiopathy and rheumatoid arthritis. She began treatment with predonisolone 40mg per day. After 20 days of steroid therapy, her hepatic function tests improved and the arthralgia symptoms disappeared. This is, to our knowledge, the first case of autoimmune cholangiopathy associated with rheumatoid arthritis, in which both symptoms improved with steroid therapy.

Original languageEnglish
Pages (from-to)1533-1534
Number of pages2
JournalHepato-gastroenterology
Volume47
Issue number36
Publication statusPublished - Dec 27 2000

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Rheumatoid Arthritis
Arthralgia
Steroids
Cholangitis
Rheumatoid Factor
Liver
Antinuclear Antibodies
Hemagglutination
Elbow
Transaminases
Serum
Hepatitis B virus
Ankle
Hepacivirus
Fingers
Alkaline Phosphatase
Knee
Therapeutics
Biopsy
Antibodies

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Ogata, H., Tsuji, H., Hashiguchi, M., Azuma, K., Shimono, J., & Fujishima, M. (2000). Autoimmune cholangiopathy associated with rheumatoid arthritis. Hepato-gastroenterology, 47(36), 1533-1534.

Autoimmune cholangiopathy associated with rheumatoid arthritis. / Ogata, Hisanobu; Tsuji, H.; Hashiguchi, M.; Azuma, K.; Shimono, J.; Fujishima, M.

In: Hepato-gastroenterology, Vol. 47, No. 36, 27.12.2000, p. 1533-1534.

Research output: Contribution to journalArticle

Ogata, H, Tsuji, H, Hashiguchi, M, Azuma, K, Shimono, J & Fujishima, M 2000, 'Autoimmune cholangiopathy associated with rheumatoid arthritis', Hepato-gastroenterology, vol. 47, no. 36, pp. 1533-1534.
Ogata H, Tsuji H, Hashiguchi M, Azuma K, Shimono J, Fujishima M. Autoimmune cholangiopathy associated with rheumatoid arthritis. Hepato-gastroenterology. 2000 Dec 27;47(36):1533-1534.
Ogata, Hisanobu ; Tsuji, H. ; Hashiguchi, M. ; Azuma, K. ; Shimono, J. ; Fujishima, M. / Autoimmune cholangiopathy associated with rheumatoid arthritis. In: Hepato-gastroenterology. 2000 ; Vol. 47, No. 36. pp. 1533-1534.
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