Autoimmune neutropenia associated with multiple sclerosis

Teruhiko Kozuka; Kensuke Kojima; Kinuyo Kaneda; Katsuto Takenaka; Yasuhiro Manabe; Yasushi Hirata; Shigenori Okuma; Hironobu Toki; Mitsune Tanimoto

doi:10.2169/internalmedicine.42.102

Autoimmune neutropenia associated with multiple sclerosis

Teruhiko Kozuka, Kensuke Kojima, Kinuyo Kaneda, Katsuto Takenaka, Yasuhiro Manabe, Yasushi Hirata, Shigenori Okuma, Hironobu Toki, Mitsune Tanimoto

Hematology, Oncology & Cardiovascular medicine

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia. The neutrophil count was consistently less than 0.2×10⁹/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor. After high-dose γ-globulin therapy was started, temporary increases in the neutrophil count were observed. Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.

Original language	English
Pages (from-to)	102-104
Number of pages	3
Journal	Internal Medicine
Volume	42
Issue number	1
DOIs	https://doi.org/10.2169/internalmedicine.42.102
Publication status	Published - Jan 1 2003

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.42.102

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abstract = "A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia. The neutrophil count was consistently less than 0.2×109/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor. After high-dose γ-globulin therapy was started, temporary increases in the neutrophil count were observed. Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.",

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AU - Kozuka, Teruhiko

AU - Kojima, Kensuke

AU - Kaneda, Kinuyo

AU - Takenaka, Katsuto

AU - Manabe, Yasuhiro

AU - Hirata, Yasushi

AU - Okuma, Shigenori

AU - Toki, Hironobu

AU - Tanimoto, Mitsune

PY - 2003/1/1

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N2 - A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia. The neutrophil count was consistently less than 0.2×109/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor. After high-dose γ-globulin therapy was started, temporary increases in the neutrophil count were observed. Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.

AB - A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia. The neutrophil count was consistently less than 0.2×109/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor. After high-dose γ-globulin therapy was started, temporary increases in the neutrophil count were observed. Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.

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Autoimmune neutropenia associated with multiple sclerosis

Abstract

All Science Journal Classification (ASJC) codes

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