Automated spectroscopic imaging of oxygen saturation in human retinal vessels

Daisuke Nakamura, S. Sueda, N. Matsuoka, Yukiyasu Yoshinaga, H. Enaida, T. Okada, Tatsuro Ishibashi

Research output: Contribution to journalConference article

3 Citations (Scopus)

Abstract

A new automatic visualization procedure for the oxygen saturation imaging from multi-spectral imaging of human retinal vessels has been proposed. Two-wavelength retinal fundus images at 545 and 560 nm, which were oxygen insensitive and oxygen sensitive, respectively, were captured by CCD cameras simultaneously through a beam splitter and interference filters. We applied a morphological processing technique to presume a distribution of incident light including the vessel parts and an optical density (OD) image of each wavelength image. And the OD ratio (OD560/OD545) image was calculated as a relative indicator of oxygen saturation. Furthermore, processing of line convergence index filter was adopted to identify the retinal vessels. Clear difference between retinal arteries and veins was observed in the automated imaging method. In addition, the decrease of oxygen saturation in the retinal artery without breathing could be monitored by the ODR. This method is possible to be applied to real-time monitoring for oxygen saturation of retinal vessels.

Original languageEnglish
Article number71631N
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7163
DOIs
Publication statusPublished - May 13 2009
EventOphthalmic Technologies XIX - San Jose, CA, United States
Duration: Jan 24 2009Jan 26 2009

Fingerprint

Retinal Vessels
vessels
Oxygen
saturation
Imaging techniques
oxygen
Retinal Artery
Density (optical)
optical density
arteries
retinal images
Retinal Vein
filters
Wavelength
beam splitters
breathing
CCD cameras
Processing
veins
wavelengths

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Automated spectroscopic imaging of oxygen saturation in human retinal vessels. / Nakamura, Daisuke; Sueda, S.; Matsuoka, N.; Yoshinaga, Yukiyasu; Enaida, H.; Okada, T.; Ishibashi, Tatsuro.

In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 7163, 71631N, 13.05.2009.

Research output: Contribution to journalConference article

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AU - Ishibashi, Tatsuro

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