Autonomic regulation of plasma insulin, glucagon and growth hormone responses to feeding in sheep fed a diet supplemented with calcium propionate

H. Sano, Y. Mori, Hideyuki Takahashi, Y. Terashima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The role of the autonomie nervous system in the regulation of plasma insulin, glucagon and growth hormone (GH) responses to supplemental propionate was investigated in rams. The rams were fed alfalfa hay cubes supplemented with 10 mmol kg-1 d-1 of calcium propionate. Saline, phentolamine, propranolol, atropine or hexamethonium were separately infused for 135 min starting 15 min before feeding. During saline infusion, the concentrations of plasma insulin and glucagon increased (P < 0.05) after the initiation of feeding, whereas plasma GH concentrations tended to decrease. Plasma insulin responses to feeding tended to be reduced by atropine and hexamethonium infusions. Plasma glucagon responses were abolished by atropine, hexamethonium and phentolamine infusions. It is suggested that in rams fed a propionate supplemented diet, the release of insulin and glucagon increases in response to feeding. Insulin release is mediated by activation of the parasympathetic nervous system, although responses were not significant in this study, while glucagon release is mediated both by activation of the parasympathetic nervous system and by the adrenergic α-receptors of the sympathetic nervous system. This study does not support a role for the autonomie nervous system in the regulation of GH release.

Original languageEnglish
Pages (from-to)449-456
Number of pages8
JournalCanadian Journal of Animal Science
Volume79
Issue number4
DOIs
Publication statusPublished - Jan 1 1999

Fingerprint

calcium propionate
sheep feeding
glucagon
Glucagon
somatotropin
Growth Hormone
Sheep
insulin
Hexamethonium
Insulin
Diet
atropine
parasympathetic nervous system
Atropine
rams
Parasympathetic Nervous System
diet
Phentolamine
Propionates
propionates

All Science Journal Classification (ASJC) codes

  • Food Animals
  • Animal Science and Zoology

Cite this

Autonomic regulation of plasma insulin, glucagon and growth hormone responses to feeding in sheep fed a diet supplemented with calcium propionate. / Sano, H.; Mori, Y.; Takahashi, Hideyuki; Terashima, Y.

In: Canadian Journal of Animal Science, Vol. 79, No. 4, 01.01.1999, p. 449-456.

Research output: Contribution to journalArticle

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