Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia

K. Ikezoe, T. Yoshimura, T. Taniwaki, E. Matsuura, H. Furuya, T. Yamada, K. Nagamatsu, Jun ichi Kira

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The proband, a 53-year-old man, developed progressive spinal and bulbar muscular atrophy and gynecomastia at the age of 50. His father had weakness of lower limbs, and his son had a nasal voice, ocular movement abnormalities, and gynecomastia, whereas two of the proband's brothers showed either gynecomastia or tongue fasciculations. None of the patients showed any expansion of CAG repeat in the androgen receptor gene or any hormonal abnormality. Thus, this family is affected by a form of autosomal dominant spinal and bulbar muscular atrophy with gynecomastia.

Original languageEnglish
Pages (from-to)2187-2189
Number of pages3
JournalNeurology
Volume53
Issue number9
Publication statusPublished - Dec 10 1999

Fingerprint

Atrophic Muscular Disorders
Gynecomastia
Eye Abnormalities
Fasciculation
Androgen Receptors
Eye Movements
Nuclear Family
Nose
Fathers
Siblings
Lower Extremity
Genes

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

Ikezoe, K., Yoshimura, T., Taniwaki, T., Matsuura, E., Furuya, H., Yamada, T., ... Kira, J. I. (1999). Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia. Neurology, 53(9), 2187-2189.

Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia. / Ikezoe, K.; Yoshimura, T.; Taniwaki, T.; Matsuura, E.; Furuya, H.; Yamada, T.; Nagamatsu, K.; Kira, Jun ichi.

In: Neurology, Vol. 53, No. 9, 10.12.1999, p. 2187-2189.

Research output: Contribution to journalArticle

Ikezoe, K, Yoshimura, T, Taniwaki, T, Matsuura, E, Furuya, H, Yamada, T, Nagamatsu, K & Kira, JI 1999, 'Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia', Neurology, vol. 53, no. 9, pp. 2187-2189.
Ikezoe K, Yoshimura T, Taniwaki T, Matsuura E, Furuya H, Yamada T et al. Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia. Neurology. 1999 Dec 10;53(9):2187-2189.
Ikezoe, K. ; Yoshimura, T. ; Taniwaki, T. ; Matsuura, E. ; Furuya, H. ; Yamada, T. ; Nagamatsu, K. ; Kira, Jun ichi. / Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia. In: Neurology. 1999 ; Vol. 53, No. 9. pp. 2187-2189.
@article{75727a5afce445178617accbdfef511a,
title = "Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia",
abstract = "The proband, a 53-year-old man, developed progressive spinal and bulbar muscular atrophy and gynecomastia at the age of 50. His father had weakness of lower limbs, and his son had a nasal voice, ocular movement abnormalities, and gynecomastia, whereas two of the proband's brothers showed either gynecomastia or tongue fasciculations. None of the patients showed any expansion of CAG repeat in the androgen receptor gene or any hormonal abnormality. Thus, this family is affected by a form of autosomal dominant spinal and bulbar muscular atrophy with gynecomastia.",
author = "K. Ikezoe and T. Yoshimura and T. Taniwaki and E. Matsuura and H. Furuya and T. Yamada and K. Nagamatsu and Kira, {Jun ichi}",
year = "1999",
month = "12",
day = "10",
language = "English",
volume = "53",
pages = "2187--2189",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Autosomal dominant familial spinal and bulbar muscular atrophy with gynecomastia

AU - Ikezoe, K.

AU - Yoshimura, T.

AU - Taniwaki, T.

AU - Matsuura, E.

AU - Furuya, H.

AU - Yamada, T.

AU - Nagamatsu, K.

AU - Kira, Jun ichi

PY - 1999/12/10

Y1 - 1999/12/10

N2 - The proband, a 53-year-old man, developed progressive spinal and bulbar muscular atrophy and gynecomastia at the age of 50. His father had weakness of lower limbs, and his son had a nasal voice, ocular movement abnormalities, and gynecomastia, whereas two of the proband's brothers showed either gynecomastia or tongue fasciculations. None of the patients showed any expansion of CAG repeat in the androgen receptor gene or any hormonal abnormality. Thus, this family is affected by a form of autosomal dominant spinal and bulbar muscular atrophy with gynecomastia.

AB - The proband, a 53-year-old man, developed progressive spinal and bulbar muscular atrophy and gynecomastia at the age of 50. His father had weakness of lower limbs, and his son had a nasal voice, ocular movement abnormalities, and gynecomastia, whereas two of the proband's brothers showed either gynecomastia or tongue fasciculations. None of the patients showed any expansion of CAG repeat in the androgen receptor gene or any hormonal abnormality. Thus, this family is affected by a form of autosomal dominant spinal and bulbar muscular atrophy with gynecomastia.

UR - http://www.scopus.com/inward/record.url?scp=0032763819&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032763819&partnerID=8YFLogxK

M3 - Article

C2 - 10599805

AN - SCOPUS:0032763819

VL - 53

SP - 2187

EP - 2189

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 9

ER -