B-Z transition of (dA-T)n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation

Hideaki Sasaki, Shigeki Sasaki

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The spermine conjugate of the cationic porphyrin ligand (1) selectively induced the B-Z transition of the [(dA-T)n]2 sequence at low salt concentrations. The [(dG-C)n]2 sequence was not transformed into the Z-form. The B-Z transition was induced via an intermediate DNA conformation, which was formed by the external binding and formation of an assembly of 1 onto B-DNA.

Original languageEnglish
Pages (from-to)9024-9026
Number of pages3
JournalChemical Communications
Volume49
Issue number79
DOIs
Publication statusPublished - Oct 11 2013

Fingerprint

B-Form DNA
Spermine
Porphyrins
Conformations
DNA
Salts
Ligands

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

B-Z transition of (dA-T)n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation. / Sasaki, Hideaki; Sasaki, Shigeki.

In: Chemical Communications, Vol. 49, No. 79, 11.10.2013, p. 9024-9026.

Research output: Contribution to journalArticle

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