B-Z transition of (dA-T)n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation

Hideaki Sasaki; Shigeki Sasaki

doi:10.1039/c3cc45213a

B-Z transition of (dA-T)_n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation

Hideaki Sasaki, Shigeki Sasaki

Chemo-Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The spermine conjugate of the cationic porphyrin ligand (1) selectively induced the B-Z transition of the [(dA-T)_n]₂ sequence at low salt concentrations. The [(dG-C)_n]₂ sequence was not transformed into the Z-form. The B-Z transition was induced via an intermediate DNA conformation, which was formed by the external binding and formation of an assembly of 1 onto B-DNA.

Original language	English
Pages (from-to)	9024-9026
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	79
DOIs	https://doi.org/10.1039/c3cc45213a
Publication status	Published - Sep 10 2013

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c3cc45213a

Cite this

@article{449ccf1a474d450e9329ab0e6527de53,

title = "B-Z transition of (dA-T)n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation",

abstract = "The spermine conjugate of the cationic porphyrin ligand (1) selectively induced the B-Z transition of the [(dA-T)n]2 sequence at low salt concentrations. The [(dG-C)n]2 sequence was not transformed into the Z-form. The B-Z transition was induced via an intermediate DNA conformation, which was formed by the external binding and formation of an assembly of 1 onto B-DNA.",

author = "Hideaki Sasaki and Shigeki Sasaki",

year = "2013",

month = sep,

day = "10",

doi = "10.1039/c3cc45213a",

language = "English",

volume = "49",

pages = "9024--9026",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "79",

}

TY - JOUR

T1 - B-Z transition of (dA-T)n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation

AU - Sasaki, Hideaki

AU - Sasaki, Shigeki

PY - 2013/9/10

Y1 - 2013/9/10

N2 - The spermine conjugate of the cationic porphyrin ligand (1) selectively induced the B-Z transition of the [(dA-T)n]2 sequence at low salt concentrations. The [(dG-C)n]2 sequence was not transformed into the Z-form. The B-Z transition was induced via an intermediate DNA conformation, which was formed by the external binding and formation of an assembly of 1 onto B-DNA.

AB - The spermine conjugate of the cationic porphyrin ligand (1) selectively induced the B-Z transition of the [(dA-T)n]2 sequence at low salt concentrations. The [(dG-C)n]2 sequence was not transformed into the Z-form. The B-Z transition was induced via an intermediate DNA conformation, which was formed by the external binding and formation of an assembly of 1 onto B-DNA.

UR - http://www.scopus.com/inward/record.url?scp=84883856664&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883856664&partnerID=8YFLogxK

U2 - 10.1039/c3cc45213a

DO - 10.1039/c3cc45213a

M3 - Article

C2 - 23979223

AN - SCOPUS:84883856664

VL - 49

SP - 9024

EP - 9026

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 79

ER -

B-Z transition of (dA-T)_n duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this