Baroreflex failure and beat-to-beat blood pressure variation

Takuya Kishi

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Hypertension has strong adverse effects on cardiovascular diseases, and increased blood pressure (BP) variability (BPV) is closely associated with the development of hypertensive organ injuries and the occurrence of cardiovascular diseases. Similar to other forms of BPV, short-term beat-to-beat BPV has also been established as a risk factor for cardiovascular diseases. Baroreflex failure is the major mechanism involved in the pathophysiology of short-term beat-to-beat BPV. Previous clinical and animal studies have demonstrated that baroreflex failure disrupted beat-to-beat BPV and hypertensive organ damage. Moreover, short-term beat-to-beat BPV was an independent determinant of vascular elasticity. Although, the clinical measurement tools and therapeutics for beat-to-beat BPV are not sufficient, we should consider that large beat-to-beat BPV is an important risk factor for cardiovascular diseases in patients with hypertension.

Original languageEnglish
Pages (from-to)547-552
Number of pages6
JournalHypertension Research
Volume41
Issue number8
DOIs
Publication statusPublished - Aug 1 2018

Fingerprint

Baroreflex
Cardiovascular Diseases
Blood Pressure
Hypertension
Elasticity
Blood Vessels
Wounds and Injuries
Therapeutics

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Baroreflex failure and beat-to-beat blood pressure variation. / Kishi, Takuya.

In: Hypertension Research, Vol. 41, No. 8, 01.08.2018, p. 547-552.

Research output: Contribution to journalReview article

Kishi, Takuya. / Baroreflex failure and beat-to-beat blood pressure variation. In: Hypertension Research. 2018 ; Vol. 41, No. 8. pp. 547-552.
@article{ceba261083764ff39d52aab7e77c87d8,
title = "Baroreflex failure and beat-to-beat blood pressure variation",
abstract = "Hypertension has strong adverse effects on cardiovascular diseases, and increased blood pressure (BP) variability (BPV) is closely associated with the development of hypertensive organ injuries and the occurrence of cardiovascular diseases. Similar to other forms of BPV, short-term beat-to-beat BPV has also been established as a risk factor for cardiovascular diseases. Baroreflex failure is the major mechanism involved in the pathophysiology of short-term beat-to-beat BPV. Previous clinical and animal studies have demonstrated that baroreflex failure disrupted beat-to-beat BPV and hypertensive organ damage. Moreover, short-term beat-to-beat BPV was an independent determinant of vascular elasticity. Although, the clinical measurement tools and therapeutics for beat-to-beat BPV are not sufficient, we should consider that large beat-to-beat BPV is an important risk factor for cardiovascular diseases in patients with hypertension.",
author = "Takuya Kishi",
year = "2018",
month = "8",
day = "1",
doi = "10.1038/s41440-018-0056-y",
language = "English",
volume = "41",
pages = "547--552",
journal = "Hypertension Research",
issn = "0916-9636",
publisher = "Nature Publishing Group",
number = "8",

}

TY - JOUR

T1 - Baroreflex failure and beat-to-beat blood pressure variation

AU - Kishi, Takuya

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Hypertension has strong adverse effects on cardiovascular diseases, and increased blood pressure (BP) variability (BPV) is closely associated with the development of hypertensive organ injuries and the occurrence of cardiovascular diseases. Similar to other forms of BPV, short-term beat-to-beat BPV has also been established as a risk factor for cardiovascular diseases. Baroreflex failure is the major mechanism involved in the pathophysiology of short-term beat-to-beat BPV. Previous clinical and animal studies have demonstrated that baroreflex failure disrupted beat-to-beat BPV and hypertensive organ damage. Moreover, short-term beat-to-beat BPV was an independent determinant of vascular elasticity. Although, the clinical measurement tools and therapeutics for beat-to-beat BPV are not sufficient, we should consider that large beat-to-beat BPV is an important risk factor for cardiovascular diseases in patients with hypertension.

AB - Hypertension has strong adverse effects on cardiovascular diseases, and increased blood pressure (BP) variability (BPV) is closely associated with the development of hypertensive organ injuries and the occurrence of cardiovascular diseases. Similar to other forms of BPV, short-term beat-to-beat BPV has also been established as a risk factor for cardiovascular diseases. Baroreflex failure is the major mechanism involved in the pathophysiology of short-term beat-to-beat BPV. Previous clinical and animal studies have demonstrated that baroreflex failure disrupted beat-to-beat BPV and hypertensive organ damage. Moreover, short-term beat-to-beat BPV was an independent determinant of vascular elasticity. Although, the clinical measurement tools and therapeutics for beat-to-beat BPV are not sufficient, we should consider that large beat-to-beat BPV is an important risk factor for cardiovascular diseases in patients with hypertension.

UR - http://www.scopus.com/inward/record.url?scp=85048103060&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048103060&partnerID=8YFLogxK

U2 - 10.1038/s41440-018-0056-y

DO - 10.1038/s41440-018-0056-y

M3 - Review article

VL - 41

SP - 547

EP - 552

JO - Hypertension Research

JF - Hypertension Research

SN - 0916-9636

IS - 8

ER -