@article{f899a39c0df843d08f7384d816b2a5a8,
title = "Base-Resolution Methylome of Retinal Pigment Epithelial Cells Used in the First Trial of Human Induced Pluripotent Stem Cell-Based Autologous Transplantation",
abstract = "In this article, Ito and colleagues delineated the base-resolution methylome of iPSC-derived retinal pigment epithelial (RPE) cell used in the first-in-human trial of autologous transplantation. The methylome closely resembled that of native RPE cell. Intriguingly, it became even closer to its natural counterpart upon xenotransplantation to mouse, demonstrating its plasticity to respond appropriately to the in vivo environment.",
author = "Hiromitsu Araki and Fumihito Miura and Akira Watanabe and Chikako Morinaga and Fumiyo Kitaoka and Yuko Kitano and Noriko Sakai and Yumiko Shibata and Motoki Terada and So Goto and Shinya Yamanaka and Masayo Takahashi and Takashi Ito",
note = "Funding Information: We appreciate the technical assistance from The Research Support Center, Research Center for Human Disease Modeling , Kyushu University Graduate School of Medical Sciences. This work was partly supported by the Japan Agency for Medical Research and Development (AMED) under grant numbers JP16am0101059 and JP18am0101103 , and by the Japan Society for the Promotion of Science (JSPS) KAKENHI 17H06305 . Funding Information: We appreciate the technical assistance from The Research Support Center, Research Center for Human Disease Modeling, Kyushu University Graduate School of Medical Sciences. This work was partly supported by the Japan Agency for Medical Research and Development (AMED) under grant numbers JP16am0101059 and JP18am0101103, and by the Japan Society for the Promotion of Science (JSPS) KAKENHI 17H06305. Publisher Copyright: {\textcopyright} 2019 The Author(s)",
year = "2019",
month = oct,
day = "8",
doi = "10.1016/j.stemcr.2019.08.014",
language = "English",
volume = "13",
pages = "761--774",
journal = "Stem Cell Reports",
issn = "2213-6711",
publisher = "Cell Press",
number = "4",
}