"Benifuuki" green tea, containing O-methylated EGCG, reduces serum low-density lipoprotein cholesterol and lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B: A double-blind, placebo-controlled randomized trial

Hisashi Imbe, Hiroyuki Sano, Masahiro Miyawaki, Reiko Fujisawa, Mai Miyasato, Fumihiko Nakatsuji, Fumitaka Haseda, Keiji Tanimoto, Jungo Terasaki, Mari Maeda-Yamamoto, Hirofumi Tachibana, Toshiaki Hanafusa

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Dyslipidaemia is a significant cardiovascular risk factor. Green tea catechins are known to have cholesterol-lowering effects. We investigated the beneficial effects of "Benifuuki," containing O-methylated catechin, on cardiovascular risk factors, specifically low-density lipoprotein (LDL) cholesterol levels. One-hundred fifty-five participants who met the inclusion criteria were divided into 3 groups: "Benifuuki," "Yabukita," or barley infusion drinkers. We evaluated the changes in parameters after 12 weeks. Serum LDL cholesterol levels in the "Benifuuki"-consuming participants were significantly lower than those in barley infusion-consuming participants without a green tea habit. Furthermore, the lectin-like oxidized low-density lipoprotein receptor-1 containing apolipoprotein B (LAB) levels in "Benifuuki" drinkers were significantly lower than those in the barley infusion group and the "Benifuuki" baseline LAB level. In participants without a green tea habit, "Benifuuki" significantly reduced the serum LDL cholesterol level and the LAB levels compared to those observed after barley infusion consumption.

Original languageEnglish
Pages (from-to)25-37
Number of pages13
JournalJournal of Functional Foods
Volume25
DOIs
Publication statusPublished - Aug 1 2016

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Class E Scavenger Receptors
apolipoprotein B
Apolipoproteins B
green tea
Tea
Hordeum
low density lipoprotein
low density lipoprotein cholesterol
lectins
LDL Cholesterol
placebos
Randomized Controlled Trials
barley
Placebos
Ligands
receptors
Catechin
Serum
Habits
risk factors

All Science Journal Classification (ASJC) codes

  • Food Science
  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

"Benifuuki" green tea, containing O-methylated EGCG, reduces serum low-density lipoprotein cholesterol and lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B : A double-blind, placebo-controlled randomized trial. / Imbe, Hisashi; Sano, Hiroyuki; Miyawaki, Masahiro; Fujisawa, Reiko; Miyasato, Mai; Nakatsuji, Fumihiko; Haseda, Fumitaka; Tanimoto, Keiji; Terasaki, Jungo; Maeda-Yamamoto, Mari; Tachibana, Hirofumi; Hanafusa, Toshiaki.

In: Journal of Functional Foods, Vol. 25, 01.08.2016, p. 25-37.

Research output: Contribution to journalArticle

Imbe, Hisashi ; Sano, Hiroyuki ; Miyawaki, Masahiro ; Fujisawa, Reiko ; Miyasato, Mai ; Nakatsuji, Fumihiko ; Haseda, Fumitaka ; Tanimoto, Keiji ; Terasaki, Jungo ; Maeda-Yamamoto, Mari ; Tachibana, Hirofumi ; Hanafusa, Toshiaki. / "Benifuuki" green tea, containing O-methylated EGCG, reduces serum low-density lipoprotein cholesterol and lectin-like oxidized low-density lipoprotein receptor-1 ligands containing apolipoprotein B : A double-blind, placebo-controlled randomized trial. In: Journal of Functional Foods. 2016 ; Vol. 25. pp. 25-37.
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