TY - JOUR
T1 - Bilayer Formation and Metal Complexation of Chiral Amphiphiles with the Cyclam Head Group
AU - Ishikawa, Yuichi
AU - Ichinose, Izumi
AU - Nishimi, Taisei
AU - Tukamoto, Masashi
AU - Kunitake, Toyoki
PY - 1990
Y1 - 1990
N2 - Chiral amphiphiles which possess a cyclic polyamine (cyclam) as the hydrophilic head group (2 C16AspC1114 N4, 2 C12GluAzoC1014 N4, C12AlaAzoCn 14 N4) were prepared, and their aggregation behavior in water was investigated by electron microscopy, differential scanning calorimetry and circular dichroism spectroscopy. These amphiphiles and their metal complexes formed bilayer membranes. The aggregate morphology, gel-to-liquid crystal phase transition and the molecular orientation depended on structures of hydrophilic and hydrophobic units of the amphiphiles. The self-organizing property of these bilayers deteriorated by replacement of the trimethylammonium head with the cyclam head and its metal complexes: -N+>-14 N4-Zn2+=-14 N4-2 H+>-14 N4-Cu2+,-14N4-Ni2+. The influence of the hydrophobic unit on self organization was as follow; C12AlaAzoCn-<2 C12GluAzoC10-<2 C16AspC11-.
AB - Chiral amphiphiles which possess a cyclic polyamine (cyclam) as the hydrophilic head group (2 C16AspC1114 N4, 2 C12GluAzoC1014 N4, C12AlaAzoCn 14 N4) were prepared, and their aggregation behavior in water was investigated by electron microscopy, differential scanning calorimetry and circular dichroism spectroscopy. These amphiphiles and their metal complexes formed bilayer membranes. The aggregate morphology, gel-to-liquid crystal phase transition and the molecular orientation depended on structures of hydrophilic and hydrophobic units of the amphiphiles. The self-organizing property of these bilayers deteriorated by replacement of the trimethylammonium head with the cyclam head and its metal complexes: -N+>-14 N4-Zn2+=-14 N4-2 H+>-14 N4-Cu2+,-14N4-Ni2+. The influence of the hydrophobic unit on self organization was as follow; C12AlaAzoCn-<2 C12GluAzoC10-<2 C16AspC11-.
UR - http://www.scopus.com/inward/record.url?scp=85016532161&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85016532161&partnerID=8YFLogxK
U2 - 10.1246/nikkashi.1990.1065
DO - 10.1246/nikkashi.1990.1065
M3 - Article
AN - SCOPUS:85016532161
SN - 0369-4577
VL - 1990
SP - 1065
EP - 1071
JO - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal
JF - Nippon Kagaku Kaishi / Chemical Society of Japan - Chemistry and Industrial Chemistry Journal
IS - 10
ER -