Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance

Hiroyuki Furusawa, Yoji Kitamura, Naoto Hagiwara, Toshiki Tsurimoto, Yoshio Okahata

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A delicate quartz crystal balance is used to measure the equilibrium constant and binding kinetics of a PCN antigen (PCNA) to double-stranded DNA model fragments. The picture illustrates how the antigen, which is negatively charged on its outer side and positively on its inside, slips along a model DNA fragment.

Original languageEnglish
Pages (from-to)446-448
Number of pages3
JournalChemPhysChem
Volume3
Issue number5
DOIs
Publication statusPublished - May 17 2002

Fingerprint

Pregnenolone Carbonitrile
toroids
Quartz crystal microbalances
antigens
quartz crystals
microbalances
strands
deoxyribonucleic acid
fragments
Antigens
Quartz
Kinetics
DNA
Equilibrium constants
kinetics
slip
Crystals

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry

Cite this

Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance. / Furusawa, Hiroyuki; Kitamura, Yoji; Hagiwara, Naoto; Tsurimoto, Toshiki; Okahata, Yoshio.

In: ChemPhysChem, Vol. 3, No. 5, 17.05.2002, p. 446-448.

Research output: Contribution to journalArticle

Furusawa, Hiroyuki ; Kitamura, Yoji ; Hagiwara, Naoto ; Tsurimoto, Toshiki ; Okahata, Yoshio. / Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance. In: ChemPhysChem. 2002 ; Vol. 3, No. 5. pp. 446-448.
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