Binding kinetics of the toroid-shaped PCNA to DNA strands on a 27 MHz quartz crystal microbalance

Hiroyuki Furusawa, Yoji Kitamura, Naoto Hagiwara, Toshiki Tsurimoto, Yoshio Okahata

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A delicate quartz crystal balance is used to measure the equilibrium constant and binding kinetics of a PCN antigen (PCNA) to double-stranded DNA model fragments. The picture illustrates how the antigen, which is negatively charged on its outer side and positively on its inside, slips along a model DNA fragment.

Original languageEnglish
Pages (from-to)446-448
Number of pages3
JournalChemPhysChem
Volume3
Issue number5
DOIs
Publication statusPublished - May 17 2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry

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