Abstract
Chiral amines are highly coveted within the fine-chemical industry and sustainable synthetic methodologies for their production are of great value. By harnessing the chirality present in cellulose-derived (–)-levoglucosenone (LGO), several bio-based sp3-rich amines containing up to four chiral centres have been readily prepared under aqueous conditions without using any catalysts, ligands, auxiliaries or resolutions.
| Original language | English |
|---|---|
| Pages (from-to) | 2028-2038 |
| Number of pages | 11 |
| Journal | European Journal of Organic Chemistry |
| Volume | 2018 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - May 8 2018 |
All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry
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Cite this
Kim, S. W., Ledingham, E. T., Kudo, S., Greatrex, B. W., & Sperry, J. (2018). Bio-Based Chiral Amines via Aza-Michael Additions to (–)-Levoglucosenone Under Aqueous Conditions. European Journal of Organic Chemistry, 2018(17), 2028-2038. https://doi.org/10.1002/ejoc.201800388