Abstract
Chiral amines are highly coveted within the fine-chemical industry and sustainable synthetic methodologies for their production are of great value. By harnessing the chirality present in cellulose-derived (–)-levoglucosenone (LGO), several bio-based sp3-rich amines containing up to four chiral centres have been readily prepared under aqueous conditions without using any catalysts, ligands, auxiliaries or resolutions.
| Original language | English |
|---|---|
| Pages (from-to) | 2028-2038 |
| Number of pages | 11 |
| Journal | European Journal of Organic Chemistry |
| Volume | 2018 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - May 8 2018 |
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All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
Bio-Based Chiral Amines via Aza-Michael Additions to (–)-Levoglucosenone Under Aqueous Conditions. / Kim, Shi Wei; Ledingham, Edward T.; Kudo, Shinji; Greatrex, Ben W.; Sperry, Jonathan.
In: European Journal of Organic Chemistry, Vol. 2018, No. 17, 08.05.2018, p. 2028-2038.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bio-Based Chiral Amines via Aza-Michael Additions to (–)-Levoglucosenone Under Aqueous Conditions
AU - Kim, Shi Wei
AU - Ledingham, Edward T.
AU - Kudo, Shinji
AU - Greatrex, Ben W.
AU - Sperry, Jonathan
PY - 2018/5/8
Y1 - 2018/5/8
N2 - Chiral amines are highly coveted within the fine-chemical industry and sustainable synthetic methodologies for their production are of great value. By harnessing the chirality present in cellulose-derived (–)-levoglucosenone (LGO), several bio-based sp3-rich amines containing up to four chiral centres have been readily prepared under aqueous conditions without using any catalysts, ligands, auxiliaries or resolutions.
AB - Chiral amines are highly coveted within the fine-chemical industry and sustainable synthetic methodologies for their production are of great value. By harnessing the chirality present in cellulose-derived (–)-levoglucosenone (LGO), several bio-based sp3-rich amines containing up to four chiral centres have been readily prepared under aqueous conditions without using any catalysts, ligands, auxiliaries or resolutions.
UR - http://www.scopus.com/inward/record.url?scp=85046550753&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85046550753&partnerID=8YFLogxK
U2 - 10.1002/ejoc.201800388
DO - 10.1002/ejoc.201800388
M3 - Article
AN - SCOPUS:85046550753
VL - 2018
SP - 2028
EP - 2038
JO - Liebigs Annalen der Chemie
JF - Liebigs Annalen der Chemie
SN - 1434-193X
IS - 17
ER -