Bio-inert Properties of TEG Modified Dendrimer Interface

Yoshiko Miura, Yuki Kojima, Hirokazu Seto, Yu Hoshino

Research output: Contribution to journalArticlepeer-review

Abstract

The bioinert interfaces that prevent adhesion of proteins and cells are important for biomaterial applications. In order to design a bioinert interface, the immobilization of an appropriate functional group and the control of molecular density is required. Dendrimer was modified with triethylene glycol (TEG) to display a dense brush structure. TEG with different density and terminal groups were immobilized with a dendrimer template and thiol terminated molecules. The inhibitory effect on protein and bacteria binding was investigated. The physical property of the interface was measured by QCM-admittance to clarify the factor of the bioinert property.

Original languageEnglish
Pages (from-to)519-523
Number of pages5
Journalanalytical sciences
Volume37
Issue number3
DOIs
Publication statusPublished - 2021

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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