Bioactive steroidal saponins from Smilax medica

M. Sautour, T. Miyamoto, Marie Aleth Lacaille-Dubois

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Two new spirostanol saponins (1 and 2) were isolated from the roots of Smilax medica, together with the known smilagenin 3-O-β-D-glucopyranoside (3). Their structures were determined by spectroscopic methods including 1D- and 2D-NMR experiments. Compounds 1 and 2 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (MICs between 6.25 and 50 μg/mL) whereas 3 was inactive.

Original languageEnglish
Pages (from-to)667-670
Number of pages4
JournalPlanta medica
Volume72
Issue number7
DOIs
Publication statusPublished - Jun 1 2006

Fingerprint

Smilax
Spirostans
steroid saponins
Candida glabrata
Candida tropicalis
Candida
Saponins
Candida albicans
saponins
Human Activities
Yeast
Yeasts
Nuclear magnetic resonance
yeasts
Experiments
methodology
sarsasapogenin

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Cite this

Bioactive steroidal saponins from Smilax medica. / Sautour, M.; Miyamoto, T.; Lacaille-Dubois, Marie Aleth.

In: Planta medica, Vol. 72, No. 7, 01.06.2006, p. 667-670.

Research output: Contribution to journalArticle

Sautour, M, Miyamoto, T & Lacaille-Dubois, MA 2006, 'Bioactive steroidal saponins from Smilax medica', Planta medica, vol. 72, no. 7, pp. 667-670. https://doi.org/10.1055/s-2006-931582
Sautour, M. ; Miyamoto, T. ; Lacaille-Dubois, Marie Aleth. / Bioactive steroidal saponins from Smilax medica. In: Planta medica. 2006 ; Vol. 72, No. 7. pp. 667-670.
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