Three new cembrane-type diterpenoids, lobophynins A (1), B (2), and C (3), were isolated from the soft coral Lobophytum schoedei. Their structures and relative stereochemistries were determined by extensive 2D NMR studies. Lobophynin C (3) has ichthyotoxicity against the mosquito fish, Oryzias latipes, and lethal activity toward brine shrimps.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Molecular Medicine
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry