Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution

Jin Ming Wu, Fan Xiao, Satoshi Hayakawa, Kanji Tsuru, Shinji Takemoto, Akiyoshi Osaka

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A simple and versatile treatment was developed to provide various metallic biomaterials such as Ti, NiTi, Ta and SUS 316L stainless steel with in vitro bioactivity or ability to deposit carbonate-incorporated apatite in a simulated body fluid (Kokubo solution). A well-crystallized anatase layer deposited on the metallic biomaterials surfaces after soaking them at 60°C for 24 h in an aqueous solution of titanium tetrafluoride (40 mM) whose pH was adjusted to 1.9 with HCl. The as-coated anatase layers did not deposit apatite. When heated at 300°C they were so bioactive as to deposit apatite within 5 day(s) in the Kokubo solution. The trace amount of fluorine weakly bound in the as-coated anatase layers was suggested to be one of the factors that suppressed the bioactivity.

Original languageEnglish
Pages (from-to)1027-1032
Number of pages6
JournalJournal of Materials Science: Materials in Medicine
Volume14
Issue number12
DOIs
Publication statusPublished - Dec 1 2003

Fingerprint

Apatites
Apatite
Biocompatible Materials
Bioactivity
Biomaterials
Titanium dioxide
Deposits
Titanium
Fluorine
Body fluids
Carbonates
Stainless Steel
Body Fluids
Stainless steel
titanium dioxide
titanium tetrafluoride

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Chemical Engineering(all)

Cite this

Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution. / Wu, Jin Ming; Xiao, Fan; Hayakawa, Satoshi; Tsuru, Kanji; Takemoto, Shinji; Osaka, Akiyoshi.

In: Journal of Materials Science: Materials in Medicine, Vol. 14, No. 12, 01.12.2003, p. 1027-1032.

Research output: Contribution to journalArticle

Wu, Jin Ming ; Xiao, Fan ; Hayakawa, Satoshi ; Tsuru, Kanji ; Takemoto, Shinji ; Osaka, Akiyoshi. / Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution. In: Journal of Materials Science: Materials in Medicine. 2003 ; Vol. 14, No. 12. pp. 1027-1032.
@article{58c3a56119e446d789b1b1fe59d7acde,
title = "Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution",
abstract = "A simple and versatile treatment was developed to provide various metallic biomaterials such as Ti, NiTi, Ta and SUS 316L stainless steel with in vitro bioactivity or ability to deposit carbonate-incorporated apatite in a simulated body fluid (Kokubo solution). A well-crystallized anatase layer deposited on the metallic biomaterials surfaces after soaking them at 60°C for 24 h in an aqueous solution of titanium tetrafluoride (40 mM) whose pH was adjusted to 1.9 with HCl. The as-coated anatase layers did not deposit apatite. When heated at 300°C they were so bioactive as to deposit apatite within 5 day(s) in the Kokubo solution. The trace amount of fluorine weakly bound in the as-coated anatase layers was suggested to be one of the factors that suppressed the bioactivity.",
author = "Wu, {Jin Ming} and Fan Xiao and Satoshi Hayakawa and Kanji Tsuru and Shinji Takemoto and Akiyoshi Osaka",
year = "2003",
month = "12",
day = "1",
doi = "10.1023/B:JMSM.0000003998.37583.d7",
language = "English",
volume = "14",
pages = "1027--1032",
journal = "Journal of Materials Science: Materials in Electronics",
issn = "0957-4522",
publisher = "Springer New York",
number = "12",

}

TY - JOUR

T1 - Bioactivity of metallic biomaterials with anatase layers deposited in acidic titanium tetrafluoride solution

AU - Wu, Jin Ming

AU - Xiao, Fan

AU - Hayakawa, Satoshi

AU - Tsuru, Kanji

AU - Takemoto, Shinji

AU - Osaka, Akiyoshi

PY - 2003/12/1

Y1 - 2003/12/1

N2 - A simple and versatile treatment was developed to provide various metallic biomaterials such as Ti, NiTi, Ta and SUS 316L stainless steel with in vitro bioactivity or ability to deposit carbonate-incorporated apatite in a simulated body fluid (Kokubo solution). A well-crystallized anatase layer deposited on the metallic biomaterials surfaces after soaking them at 60°C for 24 h in an aqueous solution of titanium tetrafluoride (40 mM) whose pH was adjusted to 1.9 with HCl. The as-coated anatase layers did not deposit apatite. When heated at 300°C they were so bioactive as to deposit apatite within 5 day(s) in the Kokubo solution. The trace amount of fluorine weakly bound in the as-coated anatase layers was suggested to be one of the factors that suppressed the bioactivity.

AB - A simple and versatile treatment was developed to provide various metallic biomaterials such as Ti, NiTi, Ta and SUS 316L stainless steel with in vitro bioactivity or ability to deposit carbonate-incorporated apatite in a simulated body fluid (Kokubo solution). A well-crystallized anatase layer deposited on the metallic biomaterials surfaces after soaking them at 60°C for 24 h in an aqueous solution of titanium tetrafluoride (40 mM) whose pH was adjusted to 1.9 with HCl. The as-coated anatase layers did not deposit apatite. When heated at 300°C they were so bioactive as to deposit apatite within 5 day(s) in the Kokubo solution. The trace amount of fluorine weakly bound in the as-coated anatase layers was suggested to be one of the factors that suppressed the bioactivity.

UR - http://www.scopus.com/inward/record.url?scp=0347380998&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0347380998&partnerID=8YFLogxK

U2 - 10.1023/B:JMSM.0000003998.37583.d7

DO - 10.1023/B:JMSM.0000003998.37583.d7

M3 - Article

C2 - 15348494

AN - SCOPUS:0347380998

VL - 14

SP - 1027

EP - 1032

JO - Journal of Materials Science: Materials in Electronics

JF - Journal of Materials Science: Materials in Electronics

SN - 0957-4522

IS - 12

ER -