Bioactivity of sol-gel derived organically modified silicates. Part I: In vitro examination

Kanji Tsuru, C. Ohtsuki, A. Osaka, T. Iwamoto, J. D. Mackenzie

Research output: Contribution to journalArticle

143 Citations (Scopus)

Abstract

Bioactivity was investigated for several organically modified silicates (Ormosils) prepared through sol-gel processes. Ca(II)-free samples were biocompatible only, but Ca(II) containing samples were bioactive and deposited apatite during immersion in a simulated body fluid. The ease of silanol (Si-OH) group formation on the ormosils was considered a predominant factor controlling the bioactivity, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the simulated body fluid is secondary.

Original languageEnglish
Pages (from-to)157-161
Number of pages5
JournalJournal of Materials Science: Materials in Medicine
Volume8
Issue number3
DOIs
Publication statusPublished - Mar 1 1997

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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