Abstract
We previously showed with computer simulations that cyclic enzyme systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation) and the applicability for a switching circuit in a biocomputer. The switching time was inevitably determined in accordance with the difference in amount between two inputs of the system. This characteristic is, however, a disadvantage for practical use of a switching device; we need to improve the system in order for the switching time to optionally be changed. We shall present here how to turn on (off) the switch independently of the modes of two inputs. By introducing pulse perturbation, we could optionally set up the switching time of a cyclic enzyme system (biochemical switching device).
| Original language | English |
|---|---|
| Pages (from-to) | 155-162 |
| Number of pages | 8 |
| Journal | BioSystems |
| Volume | 22 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jan 1 1989 |
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All Science Journal Classification (ASJC) codes
- Statistics and Probability
- Modelling and Simulation
- Biochemistry, Genetics and Molecular Biology(all)
- Applied Mathematics
Cite this
Biochemical switching device : how to turn on (off) the switch. / Okamoto, Masahiro; Sakai, Toshio; Hayashi, Katsuya.
In: BioSystems, Vol. 22, No. 2, 01.01.1989, p. 155-162.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biochemical switching device
T2 - how to turn on (off) the switch
AU - Okamoto, Masahiro
AU - Sakai, Toshio
AU - Hayashi, Katsuya
PY - 1989/1/1
Y1 - 1989/1/1
N2 - We previously showed with computer simulations that cyclic enzyme systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation) and the applicability for a switching circuit in a biocomputer. The switching time was inevitably determined in accordance with the difference in amount between two inputs of the system. This characteristic is, however, a disadvantage for practical use of a switching device; we need to improve the system in order for the switching time to optionally be changed. We shall present here how to turn on (off) the switch independently of the modes of two inputs. By introducing pulse perturbation, we could optionally set up the switching time of a cyclic enzyme system (biochemical switching device).
AB - We previously showed with computer simulations that cyclic enzyme systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation) and the applicability for a switching circuit in a biocomputer. The switching time was inevitably determined in accordance with the difference in amount between two inputs of the system. This characteristic is, however, a disadvantage for practical use of a switching device; we need to improve the system in order for the switching time to optionally be changed. We shall present here how to turn on (off) the switch independently of the modes of two inputs. By introducing pulse perturbation, we could optionally set up the switching time of a cyclic enzyme system (biochemical switching device).
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UR - http://www.scopus.com/inward/citedby.url?scp=0024504472&partnerID=8YFLogxK
U2 - 10.1016/0303-2647(89)90043-9
DO - 10.1016/0303-2647(89)90043-9
M3 - Article
C2 - 2720139
AN - SCOPUS:0024504472
VL - 22
SP - 155
EP - 162
JO - BioSystems
JF - BioSystems
SN - 0303-2647
IS - 2
ER -