Biological applications of magnetic nanoparticles-for magnetic immunoassay and magnetic particle imaging

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Here, we introduce the application of magnetic nanoparticles (MNPs) for magnetic immunoassay and magnetic particle imaging (MPI). First, we present a liquid-phase magnetic immunoassay system that uses the difference in Brownian relaxation between bound and unbound magnetic particles. We found that the minimum detectable molecular number concentration of the developed magnetic immunoassay system is 3.6 × 10-18 mol/mL. We then studied the effect of the alignment of the easy axes on the performance of the MPI. Although the detection sensitivity can be improved by using an aligned MNP sample, the spatial resolution of the aligned sample strongly depends on the direction of alignment of the easy axes.

Original languageEnglish
Title of host publicationMagnetic Materials Processes and Devices 14
EditorsC. Bonhote, H. H. Gatzen, Y. Kitamoto, G. Zangari, T. Osaka
PublisherElectrochemical Society Inc.
Pages39-47
Number of pages9
Edition2
ISBN (Electronic)9781607685395
DOIs
Publication statusPublished - Jan 1 2016
EventSymposium on Magnetic Materials Processes and Devices 14 - PRiME 2016/230th ECS Meeting - Honolulu, United States
Duration: Oct 2 2016Oct 7 2016

Publication series

NameECS Transactions
Number2
Volume75
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Other

OtherSymposium on Magnetic Materials Processes and Devices 14 - PRiME 2016/230th ECS Meeting
CountryUnited States
CityHonolulu
Period10/2/1610/7/16

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Fingerprint Dive into the research topics of 'Biological applications of magnetic nanoparticles-for magnetic immunoassay and magnetic particle imaging'. Together they form a unique fingerprint.

Cite this