Biologically active gangliosides from echinoderms

Ryuichi Higuchi, Masanori Inagaki, Koji Yamada, Tomofumi Miyamoto

Research output: Contribution to journalReview article

32 Citations (Scopus)

Abstract

This review will summarize the authors' studies on the structure and the biological activities of the gangliosides from echinoderms. Over 40 gangliosides have been obtained and characterized from 13 kinds of echinoderms, namely, Acanthaster planci, Asterina pectinifera, Asterias amurensis versicolor, Astropecten latespinosus, Luidia maculata, Linckia laevigata (starfish), Cucumaria echinata, Holothuria pervicax, H. leucospilota, Stichopus japonicus, S. chloronotus (sea cucumber), Comanthus japonica (feather star) and Ophiocoma scolopendrina (brittle star). The structural feature of the echinoderms gangliosides was their unique carbohydrate moieties. The biological property of the gangliosides from echinoderms, taking up in this review, was mainly neuritogenic activity.

Original languageEnglish
Pages (from-to)367-370
Number of pages4
JournalJournal of Natural Medicines
Volume61
Issue number4
DOIs
Publication statusPublished - Oct 1 2007

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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