Biologically active glycosides from asteroidea, 38 [(+)] glycosphingolipids from the starfish Luidia maculata, 2 [(+)] - Isolation and structure of a GM3-type ganglioside molecular species

Satoshi Kawatake, Masanori Inagaki, Tomofumi Miyamoto, Ryuichi Isobe, Ryuichi Higuchi

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Abstract

A ganglioside molecular species, LMG-2 (1), has been obtained from the water-soluble lipid fraction of the chloroform/methanol extract of the starfish Luidia maculata. On the basis of chemical and spectroscopic findings, the structure of 1 has been elucidated. 1 is a ganglioside molecular species of starfish resembling the mammalian ganglioside GM3. In addition, 1 shows neuritogenic activity toward the rat pheochromocytoma cell line PC-12 cell.

Original languageEnglish
Pages (from-to)765-769
Number of pages5
JournalEuropean Journal of Organic Chemistry
Issue number4
Publication statusPublished - Apr 1 1999

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All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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