Biomechanical evaluation of Ti-Nb-Sn alloy implants with a low young’s modulus

Kenta Takahashi, Naru Shiraishi, Risa Ishiko-Uzuka, Takahisa Anada, Osamu Suzuki, Hiroshi Masumoto, Keiichi Sasaki

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Dental implants are widely used and are a predictable treatment in various edentulous cases. Occlusal overload may be causally related to implant bone loss and a loss of integration. Stress concentrations may be diminished using a mechanobiologically integrated implant with bone tissue. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of a Ti-Nb-Sn alloy as a dental implant material. It was compared with cpTi. Cell proliferation and alkaline phosphatase (ALP) activity were quantified. To assess the degree of osseointegration, a push-in test was carried out. Cell proliferation and ALP activity in the cells grown on prepared surfaces were similar for the Ti-Nb-Sn alloy and for cpTi in all the experiments. A comparison between the Ti-Nb-Sn alloy implant and the cpTi implant revealed that no significant difference was apparent for the push-in test values. These results suggest that implants fabricated using Ti-Nb-Sn have a similar biological potential as cpTi and are capable of excellent osseointegration.

Original languageEnglish
Pages (from-to)5779-5788
Number of pages10
JournalInternational journal of molecular sciences
Volume16
Issue number3
DOIs
Publication statusPublished - Mar 12 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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