TY - JOUR
T1 - Biopex® acquires anti-washout properties by adding sodium alginate into its liquid phase
AU - Tanaka, Satoru
AU - Kishi, Tamisuke
AU - Shimogoryo, Ryoji
AU - Matsuya, Shigeki
AU - Ishikawa, Kunio
PY - 2003/9
Y1 - 2003/9
N2 - Biopex® sets upon mixing with its liquid phase due to chelate reaction between sodium succinate and calcium phosphate, then gradually transforms to apatite. As a result of apatite formation, set Biopex® shows excellent tissue responses and good osteoconductivity. However, Biopex would be washed out when the paste is exposed to body fluid before its setting reaction. Washed out cement causes an inflammatory response. In this investigation, therefore, sodium alginate was added to the liquid phase of Biopex® and its effects on washout properties and transformation to apatite were studied. We found that cement remaining ratio, an index of the anti-washout property, of the Biopex® increased by increasing the amounts of added sodium alginate to reach 100% when the liquid phase of Biopex® contained 0.6% or more sodium alginate. Biopex® gradually transformed to apatite regardless of the amount of added sodium alginate at least when the concentration of the sodium alginate in the liquid phase was 1.0% or less. It is concluded therefore, that addition of sodium alginate is very useful for Biopex® to acquire the anti-washout property.
AB - Biopex® sets upon mixing with its liquid phase due to chelate reaction between sodium succinate and calcium phosphate, then gradually transforms to apatite. As a result of apatite formation, set Biopex® shows excellent tissue responses and good osteoconductivity. However, Biopex would be washed out when the paste is exposed to body fluid before its setting reaction. Washed out cement causes an inflammatory response. In this investigation, therefore, sodium alginate was added to the liquid phase of Biopex® and its effects on washout properties and transformation to apatite were studied. We found that cement remaining ratio, an index of the anti-washout property, of the Biopex® increased by increasing the amounts of added sodium alginate to reach 100% when the liquid phase of Biopex® contained 0.6% or more sodium alginate. Biopex® gradually transformed to apatite regardless of the amount of added sodium alginate at least when the concentration of the sodium alginate in the liquid phase was 1.0% or less. It is concluded therefore, that addition of sodium alginate is very useful for Biopex® to acquire the anti-washout property.
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U2 - 10.4012/dmj.22.301
DO - 10.4012/dmj.22.301
M3 - Article
C2 - 14620996
AN - SCOPUS:1542601103
VL - 22
SP - 301
EP - 312
JO - Dental Materials Journal
JF - Dental Materials Journal
SN - 0287-4547
IS - 3
ER -