Bone and Calcium Research Update 2015. Basic mechanisms underlying calcium signaling and their biological potentiality

Yasuo Mori, Masayuki X. Mori, Motohiro Nishida

Research output: Contribution to journalReview article

Abstract

Calcium ion (Ca2+) is the only second messenger well recognized for the established biological role among various inorganic ions. When cellular Ca2+ controls diverse biological phenomena, it is regulated under exquisitely precise mechanisms. Many proteins have been identified as Ca2+ signal-regulating factors, and still new "players" are added to the repertory. In this review, we will focus on Ca2+ channels, Ca2+-binding proteins,and signaling pathways controlled by these Ca2+ signal-regulating proteins, in order to discuss on molecular bases, biological significance, and possible future developments of Ca2+ signaling.

Original languageEnglish
Pages (from-to)47-58
Number of pages12
JournalClinical calcium
Volume25
Issue number1
Publication statusPublished - Jan 1 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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