Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique

Daisuke Hara, Yasuharu Nakashima, Taishi Sato, Masanobu Hirata, Masayuki Kanazawa, Yusuke Kohno, Kensei Yoshimoto, Yusuke Yoshihara, Akihiro Nakamura, Yumiko Nakao, Yukihide Iwamoto

Research output: Contribution to journalArticle

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Abstract

The present study examined the bone bonding strength of diamond-structured porous titanium-alloy (Porous-Ti-alloy) manufactured using the electron beam-melting technique in comparison with fiber mesh-coated or rough-surfaced implants. Cylindrical implants with four different pore sizes (500, 640, 800, and 1000 μm) of Porous-Ti-alloy, titanium fiber mesh (FM), and surfaces roughened by titanium arc spray (Ti-spray) were implanted into the distal femur of rabbits. Bone bonding strength and histological bone ingrowth were evaluated at 4 and 12 weeks after implantation. The bone bonding strength of Porous-Ti-alloy implants (640 μm pore size) increased over time from 541.4 N at 4 weeks to 704.6 N at 12 weeks and was comparable to that of FM and Ti-spray implants at both weeks. No breakage of the porous structure after mechanical testing was found with Porous-Ti-alloy implants. Histological bone ingrowth that increased with implantation time occurred along the inner structure of Porous-Ti-alloy implants. There was no difference in bone ingrowth in Porous-Ti-alloy implants with pore sizes among 500, 640, and 800 μm; however, less bone ingrowth was observed with the 1000 μm pore size. These results indicated Porous-Ti-alloy implants with pore size under 800 μm provided biologically active and mechanically stable surface for implant fixation to bone, and had potential advantages for weight bearing orthopedic implants such as acetabular cups.

Original languageEnglish
Pages (from-to)1047-1052
Number of pages6
JournalMaterials Science and Engineering C
Volume59
DOIs
Publication statusPublished - Feb 1 2016

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Electron beam melting
Diamond
titanium alloys
Titanium alloys
bones
Diamonds
Bone
diamonds
melting
electron beams
Pore size
porosity
mesh
titanium
Titanium
fibers
sprayers
Fibers
implantation
Bearings (structural)

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique. / Hara, Daisuke; Nakashima, Yasuharu; Sato, Taishi; Hirata, Masanobu; Kanazawa, Masayuki; Kohno, Yusuke; Yoshimoto, Kensei; Yoshihara, Yusuke; Nakamura, Akihiro; Nakao, Yumiko; Iwamoto, Yukihide.

In: Materials Science and Engineering C, Vol. 59, 01.02.2016, p. 1047-1052.

Research output: Contribution to journalArticle

Hara, D, Nakashima, Y, Sato, T, Hirata, M, Kanazawa, M, Kohno, Y, Yoshimoto, K, Yoshihara, Y, Nakamura, A, Nakao, Y & Iwamoto, Y 2016, 'Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique', Materials Science and Engineering C, vol. 59, pp. 1047-1052. https://doi.org/10.1016/j.msec.2015.11.025
Hara, Daisuke ; Nakashima, Yasuharu ; Sato, Taishi ; Hirata, Masanobu ; Kanazawa, Masayuki ; Kohno, Yusuke ; Yoshimoto, Kensei ; Yoshihara, Yusuke ; Nakamura, Akihiro ; Nakao, Yumiko ; Iwamoto, Yukihide. / Bone bonding strength of diamond-structured porous titanium-alloy implants manufactured using the electron beam-melting technique. In: Materials Science and Engineering C. 2016 ; Vol. 59. pp. 1047-1052.
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