Bone mineral and other bone components in vertebrae evaluated by QCT and MRI

Masako Ito, Kuniaki Hayashi, Masataka Uetani, Yasuhiro Kawahara, Masafumi Ohki, Miho Yamada, Hideki Kitamori, Masaru Noguchi, Masahiro Ito

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Abstract

To evaluate the usefulness of assessing bone components using magnetic resonance imaging (MRI), the contributions of bone components, including mineral, fat and collagen, to bone mineral density (BMD) and T1 relaxation time (T1) were studied using phantoms. Excised human vertebrae were also evaluated by quantitative computed tomography (QCT) and MRI. T1 was shortened with increasing quantities of fat and collagen. In water, T1 was significantly affected by bone density, while in oil, T1 became slightly longer as bone density increased. The presence of fat and collagen caused under- and overestimations of BMD, respectively. There was good correlation between T1 and BMD in osteoporotic vertebrae and the vertebrae with long T1 showed an increased content of hematopoietic marrow and/or abnormally increased bone mineral. It was concluded that the experimental data showed that MRI can contribute to the assessment of bone quality.

Original languageEnglish
Pages (from-to)109-113
Number of pages5
JournalSkeletal Radiology
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 1 1993
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Ito, M., Hayashi, K., Uetani, M., Kawahara, Y., Ohki, M., Yamada, M., ... Ito, M. (1993). Bone mineral and other bone components in vertebrae evaluated by QCT and MRI. Skeletal Radiology, 22(2), 109-113. https://doi.org/10.1007/BF00197987