Bone mineral imaging using a digital magnification mammography system

Fukai Toyofuku, Kenji Tokumori, Yoshiharu Higashida, Hidetaka Arimura, Junji Morishita, Masafumi Ohki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The measurement of bone mineral content is important for diagnosis of demineralization diseases such as osteoporosis. A reliable method of obtaining bone mineral images using a digital magnification mammography system has been developed. The full-field digital phase contrast mammography (PCM) system, which has a molybdenum target of 0.1mm focal spot size, was used with 1.75 x magnification. We have performed several phantom experiments using aluminum step wedges (0.2 mm - 6.0 mm in thickness) and a bone mineral standard phantom composed of calcium carbonate and polyurethane (CaCO3 concentration: 26.7-939.0 mg/cm3) within a water or Lucite phantom. X-ray spectra on the exposure field are measured using a CdTe detector for evaluation of heel effect. From the equations of x-ray attenuation and the thickness of the subjects, quantitative images of both components were obtained. The quantitative images of the two components were obtained for different tube voltages of 24 kV to 39 kV. The relative accuracy was less than 2.5% for the entire aluminum thickness of 0.5 to 6.0 mm at 5 cm water thickness. Accuracy of bone mineral thickness was within 3.5% for 5cm water phantom. The magnified quantitative images of a hand phantom significantly increased the visibility of fine structures of bones. The digital magnification mammography system is useful not only for measurement of bone mineral content, but also high-resolution quantitative imaging of trabecular structure.

Original languageEnglish
Title of host publicationMedical Imaging 2008 - Physics of Medical Imaging
Volume6913
DOIs
Publication statusPublished - May 14 2008
EventMedical Imaging 2008 - Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2008Feb 21 2008

Other

OtherMedical Imaging 2008 - Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/18/082/21/08

Fingerprint

Mammography
Bone
Minerals
Imaging techniques
Aluminum
Water
X rays
Calcium carbonate
Visibility
Molybdenum
Polyurethanes
Detectors
Electric potential
Experiments

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Toyofuku, F., Tokumori, K., Higashida, Y., Arimura, H., Morishita, J., & Ohki, M. (2008). Bone mineral imaging using a digital magnification mammography system. In Medical Imaging 2008 - Physics of Medical Imaging (Vol. 6913). [691358] https://doi.org/10.1117/12.770387

Bone mineral imaging using a digital magnification mammography system. / Toyofuku, Fukai; Tokumori, Kenji; Higashida, Yoshiharu; Arimura, Hidetaka; Morishita, Junji; Ohki, Masafumi.

Medical Imaging 2008 - Physics of Medical Imaging. Vol. 6913 2008. 691358.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Toyofuku, F, Tokumori, K, Higashida, Y, Arimura, H, Morishita, J & Ohki, M 2008, Bone mineral imaging using a digital magnification mammography system. in Medical Imaging 2008 - Physics of Medical Imaging. vol. 6913, 691358, Medical Imaging 2008 - Physics of Medical Imaging, San Diego, CA, United States, 2/18/08. https://doi.org/10.1117/12.770387
Toyofuku F, Tokumori K, Higashida Y, Arimura H, Morishita J, Ohki M. Bone mineral imaging using a digital magnification mammography system. In Medical Imaging 2008 - Physics of Medical Imaging. Vol. 6913. 2008. 691358 https://doi.org/10.1117/12.770387
Toyofuku, Fukai ; Tokumori, Kenji ; Higashida, Yoshiharu ; Arimura, Hidetaka ; Morishita, Junji ; Ohki, Masafumi. / Bone mineral imaging using a digital magnification mammography system. Medical Imaging 2008 - Physics of Medical Imaging. Vol. 6913 2008.
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