Bone related cell-stimulating scaffold materials and a 3D cellular construct for hard tissue regeneration

Osamu Suzuki, Takahisa Anada

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The present article summarizes recently developed calcium phosphatebased scaffold materials that are capable of stimulating various cells involved in hard tissue formation as well as a method using newly developed cell culture devices to generate three dimensional (3D) cellular constructs. Synthetic octacalcium phosphate stimulates cellular functions of several cell types, including osteoblasts, chondrocytes, and pulp cells. The culture device promotes the easy assembly of chondrocytes in a 3D cellular construct. The scaffold materials, cellular constructs, and composite presented here are good candidates as implantable materials for the regeneration of hard tissue in bone defects depending on the severity of the tissue loss.

Original languageEnglish
Title of host publicationHyper Bio Assembler for 3D Cellular Systems
PublisherSpringer Japan
Pages261-273
Number of pages13
ISBN (Electronic)9784431552970
ISBN (Print)9784431552963
DOIs
Publication statusPublished - Jan 1 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Medicine(all)
  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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