Brain activation during processing of angry facial expressions in patients with alcohol dependency

Mi Sook Park, Sook Hee Kim, Sunju Sohn, Gap Jung Kim, Yeon Kyu Kim, Jin Hun Sohn

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

Original languageEnglish
Article number6
JournalJournal of physiological anthropology
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

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Facial Expression
facial expression
activation
Brain
brain
Alcohols
Chemical activation
alcohol
Processing
Oxygenation
Gyrus Cinguli
Prefrontal Cortex
Blood
Anger
anger
alcoholism
Alcoholism
Hypersensitivity
rating
evaluation

All Science Journal Classification (ASJC) codes

  • Human Factors and Ergonomics
  • Physiology
  • Orthopedics and Sports Medicine
  • Anthropology
  • Public Health, Environmental and Occupational Health
  • Physiology (medical)

Cite this

Brain activation during processing of angry facial expressions in patients with alcohol dependency. / Park, Mi Sook; Kim, Sook Hee; Sohn, Sunju; Kim, Gap Jung; Kim, Yeon Kyu; Sohn, Jin Hun.

In: Journal of physiological anthropology, Vol. 34, No. 1, 6, 01.01.2015.

Research output: Contribution to journalArticle

Park, Mi Sook ; Kim, Sook Hee ; Sohn, Sunju ; Kim, Gap Jung ; Kim, Yeon Kyu ; Sohn, Jin Hun. / Brain activation during processing of angry facial expressions in patients with alcohol dependency. In: Journal of physiological anthropology. 2015 ; Vol. 34, No. 1.
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