Brain activation during processing of angry facial expressions in patients with alcohol dependency

Mi Sook Park, Sook Hee Kim, Sunju Sohn, Gap Jung Kim, Yeon Kyu Kim, Jin Hun Sohn

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    Background: Alcoholism is associated with abnormal anger processing. The purpose of this study was to investigate brain regions involved in the evaluation of angry facial expressions in patients with alcohol dependency.Methods: Brain blood-oxygenation-level-dependent (BOLD) responses to angry faces were measured and compared between patients with alcohol dependency and controls.Results: During intensity ratings of angry faces, significant differences in BOLD were observed between patients with alcohol dependency and controls. That is, patients who were alcohol-dependent showed significantly greater activation in several brain regions, including the dorsal anterior cingulate cortex (dACC) and medial prefrontal cortex (MPFC).Conclusions: Following exposure to angry faces, abnormalities in dACC and MPFC activation in patients with alcohol dependency indicated possible inefficiencies or hypersensitivities in social cognitive processing.

    Original languageEnglish
    Article number6
    JournalJournal of physiological anthropology
    Volume34
    Issue number1
    DOIs
    Publication statusPublished - 2015

    All Science Journal Classification (ASJC) codes

    • Human Factors and Ergonomics
    • Physiology
    • Orthopedics and Sports Medicine
    • Anthropology
    • Public Health, Environmental and Occupational Health
    • Physiology (medical)

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