Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp.

Chiaki Tanaka, Yumiko Yamamoto, Masahito Otsuka, Junichi Tanaka, Toshio Ichiba, Gerard Marriott, Rachmaniar Rachmat, Tatsuo Higa

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Eight new briarane diterpenes (1-4, 7-10) have been isolated from two species of octocorals and the structures elucidated by spectroscopic analysis. Two diterpenes (2, 3) from the gorgonian Ellisella sp. inhibited cytokinesis, causing multinuclei formation on NBT-II cells, while a known briarane (12) from the sea pen Pteroeides sp. showed reversal of multidrug resistance.

Original languageEnglish
Pages (from-to)1368-1373
Number of pages6
JournalJournal of Natural Products
Volume67
Issue number8
DOIs
Publication statusPublished - Aug 1 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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  • Cite this

    Tanaka, C., Yamamoto, Y., Otsuka, M., Tanaka, J., Ichiba, T., Marriott, G., Rachmat, R., & Higa, T. (2004). Briarane diterpenes from two species of octocorals, Ellisella sp. and Pteroeides sp. Journal of Natural Products, 67(8), 1368-1373. https://doi.org/10.1021/np049923o