Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection

S. Nagafuchi, H. Ishibashi, K. Anzai, K. Ohshima, Y. Ohno, N. Fukushima, M. Hashizume, K. Sugimachi, H. Chuman, M. Kikuchi, Y. Niho

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Abstract

A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.

Original languageEnglish
Pages (from-to)883-886
Number of pages4
JournalThe Clinical Investigator
Volume72
Issue number11
DOIs
Publication statusPublished - Nov 1994

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Nagafuchi, S., Ishibashi, H., Anzai, K., Ohshima, K., Ohno, Y., Fukushima, N., Hashizume, M., Sugimachi, K., Chuman, H., Kikuchi, M., & Niho, Y. (1994). Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection. The Clinical Investigator, 72(11), 883-886. https://doi.org/10.1007/BF00190746