Calculation of metabolic flow of xylose in Lactococcus lactis

Hitomi Ohara, Michiko Owaki, Kenji Sonomoto

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A circuit diagram is proposed on the basis of an analysis of metabolic pathways of lactic acid bacteria, namely, a phosphoketolase pathway and a pentose phosphate/glycolic pathway. An augmented matrix was derived from carbon balances and stoichiometries from the circuit diagram, and solved by Gaussian elimination. Results indicated that 70% of the amount of xylose was metabolized through the pentose phosphate/glycolic pathway and that the yield of lactic acid from xylose ranged from 0.34 to 0.52 (mol/mol), whereas that of pyruvic acid was more than 1.4 (mol/mol).

Original languageEnglish
Pages (from-to)92-94
Number of pages3
JournalJournal of Bioscience and Bioengineering
Volume103
Issue number1
DOIs
Publication statusPublished - Jan 1 2007

Fingerprint

Pentoses
Pentose Phosphate Pathway
Lactococcus lactis
Xylose
phosphoketolase
Lactic acid
Lactic Acid
Phosphates
Networks (circuits)
Metabolic Networks and Pathways
Pyruvic Acid
Stoichiometry
Bacteria
Carbon
Acids

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

Cite this

Calculation of metabolic flow of xylose in Lactococcus lactis. / Ohara, Hitomi; Owaki, Michiko; Sonomoto, Kenji.

In: Journal of Bioscience and Bioengineering, Vol. 103, No. 1, 01.01.2007, p. 92-94.

Research output: Contribution to journalArticle

Ohara, Hitomi ; Owaki, Michiko ; Sonomoto, Kenji. / Calculation of metabolic flow of xylose in Lactococcus lactis. In: Journal of Bioscience and Bioengineering. 2007 ; Vol. 103, No. 1. pp. 92-94.
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