TY - JOUR
T1 - Cancer stem cells depend on their own niche
AU - Kano, Yoshihiro
AU - Ishii, Hideshi
AU - Konno, Masamitsu
AU - Ohta, Katsuya
AU - Nishikawa, Shimpei
AU - Fukusumi, Takahito
AU - Hamabe, Atsushi
AU - Hasegawa, Shinichiro
AU - Ogawa, Hisataka
AU - Ozaki, Miyuki
AU - Noguchi, Yuko
AU - Sakai, Daisuke
AU - Haraguchi, Naotsugu
AU - Kudo, Toshihiro
AU - Satoh, Taroh
AU - Doki, Yuichiro
AU - Mori, Masaki
PY - 2013/4
Y1 - 2013/4
N2 - It is considered that cancer stem cells have the same characteristics as normal stem cells, such as drug-resistance, self--renewal, differentiation, and tissue-formation. Normal stem cells depend on their surroundings, a niche. Cancer stem cells may also depend on their own niche. Because cancer stem cells are resistant to present remedies, it is important to find a remedy targeting cancer stem cells. The remedy must not only target cancer stem cells themselves but also target the niche surrounding the cancer stem cells.
AB - It is considered that cancer stem cells have the same characteristics as normal stem cells, such as drug-resistance, self--renewal, differentiation, and tissue-formation. Normal stem cells depend on their surroundings, a niche. Cancer stem cells may also depend on their own niche. Because cancer stem cells are resistant to present remedies, it is important to find a remedy targeting cancer stem cells. The remedy must not only target cancer stem cells themselves but also target the niche surrounding the cancer stem cells.
UR - http://www.scopus.com/inward/record.url?scp=84879311144&partnerID=8YFLogxK
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M3 - Review article
C2 - 23848007
AN - SCOPUS:84879311144
VL - 40
SP - 419
EP - 423
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
SN - 0385-0684
IS - 4
ER -