Abstract
Background: Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare.Case report: A 55-year-old male patient presented with an asymptomatic mass of the upper lip that had noticed 8 years previously. The mass was clinically suspected to be a benign salivary gland tumor based on palpation and magnetic resonance imaging findings. A needle biopsy was then carried out, and the pathological diagnosis was pleomorphic adenoma. The tumor was removed under general anesthesia. Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. However, SCC tissue with several mitotic figures was found in the central area of the tumor tissue. The tumor was finally diagnosed as CXPA. There was no evidence of recurrence or metastasis 6 years postoperatively.Conclusion: This is the first report of CXPA of the upper lip with an unusual malignant component of SCC.
| Original language | English |
|---|---|
| Article number | 234 |
| Journal | World Journal of Surgical Oncology |
| Volume | 11 |
| DOIs | |
| Publication status | Published - Sep 17 2013 |
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All Science Journal Classification (ASJC) codes
- Surgery
- Oncology
Cite this
Carcinoma ex pleomorphic adenoma of the upper lip : A case of an unusual malignant component of squamous cell carcinoma. / Mitate, Eiji; Kawano, Shintarou; Kiyoshima, Tamotsu; Kawazu, Toshiyuki; Chikui, Toru; Goto, Yuichi; Matsubara, Ryota; Nakamura, Seiji.
In: World Journal of Surgical Oncology, Vol. 11, 234, 17.09.2013.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Carcinoma ex pleomorphic adenoma of the upper lip
T2 - A case of an unusual malignant component of squamous cell carcinoma
AU - Mitate, Eiji
AU - Kawano, Shintarou
AU - Kiyoshima, Tamotsu
AU - Kawazu, Toshiyuki
AU - Chikui, Toru
AU - Goto, Yuichi
AU - Matsubara, Ryota
AU - Nakamura, Seiji
PY - 2013/9/17
Y1 - 2013/9/17
N2 - Background: Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare.Case report: A 55-year-old male patient presented with an asymptomatic mass of the upper lip that had noticed 8 years previously. The mass was clinically suspected to be a benign salivary gland tumor based on palpation and magnetic resonance imaging findings. A needle biopsy was then carried out, and the pathological diagnosis was pleomorphic adenoma. The tumor was removed under general anesthesia. Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. However, SCC tissue with several mitotic figures was found in the central area of the tumor tissue. The tumor was finally diagnosed as CXPA. There was no evidence of recurrence or metastasis 6 years postoperatively.Conclusion: This is the first report of CXPA of the upper lip with an unusual malignant component of SCC.
AB - Background: Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare.Case report: A 55-year-old male patient presented with an asymptomatic mass of the upper lip that had noticed 8 years previously. The mass was clinically suspected to be a benign salivary gland tumor based on palpation and magnetic resonance imaging findings. A needle biopsy was then carried out, and the pathological diagnosis was pleomorphic adenoma. The tumor was removed under general anesthesia. Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. However, SCC tissue with several mitotic figures was found in the central area of the tumor tissue. The tumor was finally diagnosed as CXPA. There was no evidence of recurrence or metastasis 6 years postoperatively.Conclusion: This is the first report of CXPA of the upper lip with an unusual malignant component of SCC.
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U2 - 10.1186/1477-7819-11-234
DO - 10.1186/1477-7819-11-234
M3 - Article
VL - 11
JO - World Journal of Surgical Oncology
JF - World Journal of Surgical Oncology
SN - 1477-7819
M1 - 234
ER -