Carcinoma of the lower uterine segment: Clinicopathologic analysis of 12 cases

Toru Hachisuga, Tsunehisa Kaku, Munetoma Enjoji

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Clinicopathologic features of 12 tumors of the lower uterine segment (isthmus) were studied and the findings compared with data on 196 tumors of the corpus endometrium proper. The mean age of these Japanese patients with tumors of the isthmus was 47 years and that of the patients with tumors of the corpus endometrium was 55 years. Seven of the isthmic tumors (58%) were graded as 3 (poorly differentiated) with histologic features of adenosquamous carcinoma, and all 12 tumors showed myometrial invasion. Endometrial hyperplasia or atypical endometrial glands were found in the endometrium adjacent to the tumor in 11 women. Normal mucosal structures of the lower uterine segment were uninvolved, in the area between the tumor and the endocervix, in only three patients. Four patients died of the disease within 36 months after surgery. In a comparison with the usual endometrial tumors of the corpus, tumors of the lower uterine segment tended to be high-grade adenosquamous carcinomas and myometrial invasion was more extensive. The short-term follow-up revealed that lower uterine segment tumors carried an unfavorable prognosis.

Original languageEnglish
Pages (from-to)26-35
Number of pages10
JournalInternational Journal of Gynecological Pathology
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 1 1989

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Carcinoma
Neoplasms
Endometrium
Adenosquamous Carcinoma
Endometrial Hyperplasia

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Obstetrics and Gynaecology

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Carcinoma of the lower uterine segment : Clinicopathologic analysis of 12 cases. / Hachisuga, Toru; Kaku, Tsunehisa; Enjoji, Munetoma.

In: International Journal of Gynecological Pathology, Vol. 8, No. 1, 01.01.1989, p. 26-35.

Research output: Contribution to journalArticle

Hachisuga, Toru ; Kaku, Tsunehisa ; Enjoji, Munetoma. / Carcinoma of the lower uterine segment : Clinicopathologic analysis of 12 cases. In: International Journal of Gynecological Pathology. 1989 ; Vol. 8, No. 1. pp. 26-35.
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