Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production

Naoki Tsukamoto, Toshio Hirakawa, Keita Matsukuma, Tsunehisa Kaku, Toshitaka Matsuyama, Toshiharu Kamura, Toshiaki Saito

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This is a report of a calcitonin-producing cervical cancer with variegated histological patterns. The levels of calcitonin correlated with the clinical course. Multiple lung metastases were completely controlled by cisplatin/Adriamycin/cyclophasphamide combination chemotherapy, although only for a short period. Microscopically, the tumor showed dominant small cell carcinoma; however, it did show differentiation into large cell nonkeratinizing carcinoma, keratinizing carcinoma, adenocarcinoma, and possibly carcinoid. Ultrastructural study revealed a few dense core secretory granules. Multiple immunohistochemical studies were performed. It is presumed that the tumor originated from the totipotent, immature precursor cells in the cervix and differentiated into endocrine carcinoma, squamous cell cancer, and adenocarcinoma.

Original languageEnglish
Pages (from-to)395-399
Number of pages5
JournalGynecologic Oncology
Volume33
Issue number3
DOIs
Publication statusPublished - Jan 1 1989

Fingerprint

Calcitonin
Cervix Uteri
Adenocarcinoma
Carcinoma
Large Cell Carcinoma
Squamous Cell Neoplasms
Small Cell Carcinoma
Carcinoid Tumor
Secretory Vesicles
Combination Drug Therapy
Uterine Cervical Neoplasms
Doxorubicin
Cisplatin
Neoplasms
Neoplasm Metastasis
Lung

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Tsukamoto, N., Hirakawa, T., Matsukuma, K., Kaku, T., Matsuyama, T., Kamura, T., & Saito, T. (1989). Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production. Gynecologic Oncology, 33(3), 395-399. https://doi.org/10.1016/0090-8258(89)90537-4

Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production. / Tsukamoto, Naoki; Hirakawa, Toshio; Matsukuma, Keita; Kaku, Tsunehisa; Matsuyama, Toshitaka; Kamura, Toshiharu; Saito, Toshiaki.

In: Gynecologic Oncology, Vol. 33, No. 3, 01.01.1989, p. 395-399.

Research output: Contribution to journalArticle

Tsukamoto, N, Hirakawa, T, Matsukuma, K, Kaku, T, Matsuyama, T, Kamura, T & Saito, T 1989, 'Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production', Gynecologic Oncology, vol. 33, no. 3, pp. 395-399. https://doi.org/10.1016/0090-8258(89)90537-4
Tsukamoto, Naoki ; Hirakawa, Toshio ; Matsukuma, Keita ; Kaku, Tsunehisa ; Matsuyama, Toshitaka ; Kamura, Toshiharu ; Saito, Toshiaki. / Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production. In: Gynecologic Oncology. 1989 ; Vol. 33, No. 3. pp. 395-399.
@article{f72ed9e8cd8b4e2788ddf9ceafe51edd,
title = "Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production",
abstract = "This is a report of a calcitonin-producing cervical cancer with variegated histological patterns. The levels of calcitonin correlated with the clinical course. Multiple lung metastases were completely controlled by cisplatin/Adriamycin/cyclophasphamide combination chemotherapy, although only for a short period. Microscopically, the tumor showed dominant small cell carcinoma; however, it did show differentiation into large cell nonkeratinizing carcinoma, keratinizing carcinoma, adenocarcinoma, and possibly carcinoid. Ultrastructural study revealed a few dense core secretory granules. Multiple immunohistochemical studies were performed. It is presumed that the tumor originated from the totipotent, immature precursor cells in the cervix and differentiated into endocrine carcinoma, squamous cell cancer, and adenocarcinoma.",
author = "Naoki Tsukamoto and Toshio Hirakawa and Keita Matsukuma and Tsunehisa Kaku and Toshitaka Matsuyama and Toshiharu Kamura and Toshiaki Saito",
year = "1989",
month = "1",
day = "1",
doi = "10.1016/0090-8258(89)90537-4",
language = "English",
volume = "33",
pages = "395--399",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "3",

}

TY - JOUR

T1 - Carcinoma of the uterine cervix with variegated histological patterns and calcitonin production

AU - Tsukamoto, Naoki

AU - Hirakawa, Toshio

AU - Matsukuma, Keita

AU - Kaku, Tsunehisa

AU - Matsuyama, Toshitaka

AU - Kamura, Toshiharu

AU - Saito, Toshiaki

PY - 1989/1/1

Y1 - 1989/1/1

N2 - This is a report of a calcitonin-producing cervical cancer with variegated histological patterns. The levels of calcitonin correlated with the clinical course. Multiple lung metastases were completely controlled by cisplatin/Adriamycin/cyclophasphamide combination chemotherapy, although only for a short period. Microscopically, the tumor showed dominant small cell carcinoma; however, it did show differentiation into large cell nonkeratinizing carcinoma, keratinizing carcinoma, adenocarcinoma, and possibly carcinoid. Ultrastructural study revealed a few dense core secretory granules. Multiple immunohistochemical studies were performed. It is presumed that the tumor originated from the totipotent, immature precursor cells in the cervix and differentiated into endocrine carcinoma, squamous cell cancer, and adenocarcinoma.

AB - This is a report of a calcitonin-producing cervical cancer with variegated histological patterns. The levels of calcitonin correlated with the clinical course. Multiple lung metastases were completely controlled by cisplatin/Adriamycin/cyclophasphamide combination chemotherapy, although only for a short period. Microscopically, the tumor showed dominant small cell carcinoma; however, it did show differentiation into large cell nonkeratinizing carcinoma, keratinizing carcinoma, adenocarcinoma, and possibly carcinoid. Ultrastructural study revealed a few dense core secretory granules. Multiple immunohistochemical studies were performed. It is presumed that the tumor originated from the totipotent, immature precursor cells in the cervix and differentiated into endocrine carcinoma, squamous cell cancer, and adenocarcinoma.

UR - http://www.scopus.com/inward/record.url?scp=0024399973&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024399973&partnerID=8YFLogxK

U2 - 10.1016/0090-8258(89)90537-4

DO - 10.1016/0090-8258(89)90537-4

M3 - Article

C2 - 2542143

AN - SCOPUS:0024399973

VL - 33

SP - 395

EP - 399

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 3

ER -