Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement.

Alisa Klaipetch, Osamu Manabe, Noriko Oyama-Manabe, Satoru Chiba, Masanao Naya, Shiro Yamada, Kenji Hirata, Hiroyuki Tsutsui, Nagara Tamaki

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Abstract

We report the usefulness of F-FDG PET/CT for the detection and therapy evaluation of the infective vegetation. A 64-year-old man with history of aortic valve replacement presented with 2 months of fever without identifiable cause. Echocardiogram showed no inflammation vegetation or abnormality of mechanical valve function. FDG PET/CT with 50 IU/kg IV heparin revealed focal uptakes near the mechanical aortic valve. After antibiotics therapy, fever was ameliorated, and FDG PET/CT findings showed markedly decreased uptake of the lesions. FDG PET/CT is a powerful tool to detect endocarditis even in patients with no anatomical abnormalities.

Original languageEnglish
Pages (from-to)1184-1185
Number of pages2
JournalClinical nuclear medicine
Volume37
Issue number12
Publication statusPublished - Jan 1 2012
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Klaipetch, A., Manabe, O., Oyama-Manabe, N., Chiba, S., Naya, M., Yamada, S., ... Tamaki, N. (2012). Cardiac (18)F-FDG PET/CT with heparin detects infective vegetation in a patient with mechanical valve replacement. Clinical nuclear medicine, 37(12), 1184-1185.